Senior Biologics Process Engineer - Greenfield GMP

Eli Lilly and Company; Indianapolis (IN); On-site; USD 68,000 - 174,000; Full time

Job summary

Eli Lilly and Company is seeking a Senior Process Engineer for the new Lebanon, Indiana, facility startup focused on biologics drug substance manufacturing. The role involves solving process challenges across upstream and downstream operations, ensuring safety, quality, and regulatory alignment.

The successful candidate will work with diverse teams to scale processes, optimize performance, and support regulatory submissions while growing with a leading global healthcare company.

Qualifications

• BS or MS in chemical engineering, biochemical engineering, or related discipline and a minimum of 2 years of experience in pharma/biotech/CMO supporting biologics process engineering.
• Experience with upstream and/or downstream biologics unit operations (bioreactors, media prep, centrifugation, chromatography or filtration).
• Authorized to work in the United States on a full‑time basis; Lilly does not sponsor visa work authorization.

Responsibilities

• Perform impact and risk assessments for unit operations.
• Learn the lab and plant reactor design, automation recipes, and procedures.
• Ensure safety and compliance with company policies and quality systems.
• Maintain equipment compliance with internal Quality System and cGMP requirements.
• Engage with cross-functional teams (HSE, QA, Tech Services, Operations, Automation).
• Prepare, review, or approve technical reports supporting design, qualification, and validation.

Skills

Biologics ops

Cell culture/fermentation

Chromatography

Filtration

Upstream/downstream

Education

BS or MS in chemical/biochemical engineering

Tools

DeltaV

Bioreactor SCADA

Dynochem

Aspen

Electronic lab notebooks

Job description

Eli Lilly and Company is seeking a Senior Process Engineer for the new Lebanon, Indiana, facility startup focused on biologics drug substance manufacturing. The role involves solving process challenges across upstream and downstream operations, ensuring safety, quality, and regulatory alignment.

The successful candidate will work with diverse teams to scale processes, optimize performance, and support regulatory submissions while growing with a leading global healthcare company.