Senior Bioinformatics Scientist, ctDNA & MRD (Remote)

Wishalicious; San Diego (CA); Hybrid; USD 150,000 - 180,000; Full time

Job summary

Wishalicious in San Diego, CA / Remote (US) seeks a Senior Bioinformatics Scientist to lead the development of ctDNA MRD assays in a regulated, collaborative setting. You will shape strategy, supervise analytical studies, and build scalable pipelines for QC, variant calling, and reporting.

The ideal candidate holds a PhD in a quantitative field (or MS with strong industry experience), has 6+ years in biotech or diagnostics, and is proficient in Python.

Qualifications

• PhD in Bioinformatics or related field, or MS with strong industry experience.
• 6+ years in biotech, diagnostics, or regulated healthcare environments.
• Hands-on experience developing NGS-based clinical assays, including ctDNA and MRD.

Responsibilities

• Lead bioinformatics strategy, development, optimization, and validation for MRD diagnostic assays.
• Design and execute analytical studies evaluating assay performance (sensitivity, accuracy, reproducibility, LOD).
• Develop and maintain scalable bioinformatics pipelines for QC, variant calling, MRD detection, and reporting.
• Collaborate with assay development, clinical, quality, regulatory, software, and data science teams to deliver validated solutions.
• Mentor junior scientists and contribute to technical documentation, audits, and regulatory submissions.

Skills

Bioinformatics

NGS analysis

Regulatory awareness

Education

PhD in Bioinformatics or related field

MS with industry experience

Tools

Python

Job description

Wishalicious in San Diego, CA / Remote (US) seeks a Senior Bioinformatics Scientist to lead the development of ctDNA MRD assays in a regulated, collaborative setting. You will shape strategy, supervise analytical studies, and build scalable pipelines for QC, variant calling, and reporting.

The ideal candidate holds a PhD in a quantitative field (or MS with strong industry experience), has 6+ years in biotech or diagnostics, and is proficient in Python.