Senior Antibody Discovery Scientist (Remote)

Takeda Pharmaceutical Co.; Boston (MA); Hybrid; USD 90,000 - 141,000; Full time

Job summary

Takeda Development Center Americas, Inc. is seeking a Research Senior Associate to design and execute in vitro antibody discovery campaigns using full-length IgG yeast display and phage display platforms, leading end-to-end discovery including library construction, FACS strategies, sequencing analysis, and hit confirmation.

Collaboration with computational teams and data-driven decision making are key. The role involves Python scripting, data visualization, NGS analysis, and multi-stage

Qualifications

• Master’s degree in biochemistry, immunology, or related field plus required experience in antibody discovery.
• Experience leading end-to-end antibody discovery campaigns and phage display initiatives.

Responsibilities

• Design and lead antibody discovery campaigns including library construction and panning strategies.
• Develop and apply Python-based scripts for data visualization and analysis of screening data.
• Perform NGS analysis, clone enrichment, and hit confirmation across multiple rounds.
• Contribute to lead optimization with a focus on developability and affinity.

Skills

Antibody discovery

Phage display

FACS

NGS data analysis

Cloning & mutagenesis

Education

Master’s degree in Biochemistry/Immunology/Molecular Biology/Bioengineering or related field

Tools

Python

FlowJo

GraphPad Prism

PyMOL

Geneious Prime

Job description

Takeda Development Center Americas, Inc. is seeking a Research Senior Associate to design and execute in vitro antibody discovery campaigns using full-length IgG yeast display and phage display platforms, leading end-to-end discovery including library construction, FACS strategies, sequencing analysis, and hit confirmation.

Collaboration with computational teams and data-driven decision making are key. The role involves Python scripting, data visualization, NGS analysis, and multi-stage