Senior Antibody Discovery Scientist

Takeda Pharmaceutical Co.; Boston (MA); Hybrid; USD 90,000 - 141,000; Full time

Job summary

Takeda Development Center Americas, Inc. is hiring a Research Senior Associate to design and lead antibody discovery campaigns using full-length IgG yeast display and phage display methods.

The role involves collaboration with computational teams, development of Python scripts, and leading multi-stage discovery from target validation to lead progression. Responsibilities include library construction, FACS strategy, sequencing analysis, clone triage, hit confirmation, and applying developability

Qualifications

• Master’s degree in Biochemistry, Biotechnology, Molecular Biology, Immunology, Bioengineering, or related field plus 30 months of related experience.
• Design and execute end-to-end antibody discovery campaigns on phage display and yeast display platforms.
• Experience with NGS library prep, data analysis, and flow cytometry for screening and hit confirmation.

Responsibilities

• Design and execute in vitro antibody discovery campaigns using IgG yeast and phage display platforms.
• Lead end-to-end discovery campaigns including library construction, FACS strategy, sequencing analysis, and hit confirmation.
• Develop Python scripts, data visualization tools, and AI-enabled workflows for high-throughput screening and sequence-function analysis.

Skills

Antibody discovery

Phage display

Yeast display

FACS

NGS analysis

Python scripting

Data visualization

Flow cytometry

Molecular cloning

Gibson assembly

Education

Master’s degree in Biochemistry/related field

Tools

IgBLAST

PyMOL

Geneious Prime

SnapGene

FlowJo

GraphPad Prism

Job description

Takeda Development Center Americas, Inc. is hiring a Research Senior Associate to design and lead antibody discovery campaigns using full-length IgG yeast display and phage display methods.

The role involves collaboration with computational teams, development of Python scripts, and leading multi-stage discovery from target validation to lead progression. Responsibilities include library construction, FACS strategy, sequencing analysis, clone triage, hit confirmation, and applying developability