Scientist, Lentiviral Vectors & CAR-T Research

Rose International; South San Francisco (CA); On-site; USD 100,000 - 140,000; Full time

Job summary

Rose International is seeking a scientifically curious Scientist for a contingent position in cell therapy research. The role focuses on hands-on lentiviral vector production, vector characterization, and analytical assay development for in vivo and in vitro applications.

The candidate will generate materials for preclinical studies, collaborate across teams, and maintain rigorous records while adhering to biosafety standards. Excellent data interpretation and communication are essential.

Qualifications

• Bachelors or Masters with at least 5 years of hands-on experience in biotechnology or cell therapy.
• PhD strongly preferred in immunology, virology, molecular biology, bioengineering, or related field.

Responsibilities

• Execute and optimize research-scale lentiviral vector production workflows.
• Produce and characterize research-grade lentiviral vectors for in vitro evaluation and preclinical studies.
• Develop and optimize molecular and cell-based assays to assess vector quality, titer, gene delivery, and CAR expression.
• Perform primary human cell culture and engineering studies to evaluate delivery platforms.
• Apply flow cytometry to assess transduction efficiency, CAR expression, and cell phenotype.
• Collaborate with project teams to define material requirements and coordinate production timelines.
• Independently plan experiments and troubleshoot technical challenges with team input.
• Analyze and present findings at internal scientific meetings with clear summaries.

Skills

Lentiviral vector production

Flow cytometry

Molecular assays

Cell culture (T cells)

Data interpretation

Education

Bachelors/Masters with 5 years industry experience

PhD in Immunology/Virology/ Molecular Biology/ Bioengineering/Cell Biology

Tools

FlowJo

GraphPad Prism

Benchling

Job description

Rose International is seeking a scientifically curious Scientist for a contingent position in cell therapy research. The role focuses on hands-on lentiviral vector production, vector characterization, and analytical assay development for in vivo and in vitro applications.

The candidate will generate materials for preclinical studies, collaborate across teams, and maintain rigorous records while adhering to biosafety standards. Excellent data interpretation and communication are essential.