Scientist II: Lentiviral Vector Production & Analysis

R&D Partners; South San Francisco (CA); Presencial; USD 84.000 - 87.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Medical insurance

401k plan

Employee Assistance Program

Long-term disability

Weekly payroll

Online timecard approval

Descripción de la vacante

R&D Partners in South San Francisco, CA is seeking a Scientist II for a 12-month contract focused on research-scale lentiviral vector production, characterization, and assay development. The role supports preclinical in vivo studies through collaboration with teams, with no animal studies conducted by the candidate.

The successful candidate will have strong experimental judgment, hands-on vector production expertise, and cell-based analytics, contributing to advancing research programs in a

Formación

• Bachelor's degree with 5+ years of industry experience or PhD in a related field.
• Hands-on experience with lentiviral vector production and characterization.
• Proficiency in aseptic mammalian cell culture and primary human immune cells (preferably T cells).
• Experience developing, optimizing, and troubleshooting molecular or cell-based analytical assays.
• Technical proficiency in flow cytometry and quantitative assay platforms (qPCR/ddPCR).
• Ability to design experiments independently and interpret data.

Responsabilidades

• Execute and optimize research-scale lentiviral vector production workflows, including suspension culture transitions.
• Produce and characterize research-grade lentiviral vectors for in vitro evaluation and preclinical studies.
• Develop, optimize, and execute molecular and cell-based assays to assess vector quality, titer, and functional activity.
• Perform primary human cell culture and engineering studies to support delivery platforms for in vivo applications.
• Apply flow cytometry to assess transduction efficiency, CAR expression, and cell phenotype.
• Collaborate with project teams to define material requirements and production timelines.

Conocimientos

Lentiviral vector production

Cell-based analytics

Flow cytometry

Experimental design

Data interpretation

Collaboration

Educación

Bachelor's degree in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology, or related

PhD in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology, or related

Herramientas

qPCR

ddPCR

Flow cytometer

Descripción del empleo

R&D Partners in South San Francisco, CA is seeking a Scientist II for a 12-month contract focused on research-scale lentiviral vector production, characterization, and assay development. The role supports preclinical in vivo studies through collaboration with teams, with no animal studies conducted by the candidate.

The successful candidate will have strong experimental judgment, hands-on vector production expertise, and cell-based analytics, contributing to advancing research programs in a