Scientist - LC-MS

Creative Solutions Services, LLC; Thousand Oaks (CA); On-site; USD 52,000 - 58,000; Part time

Benefits offered by this job

Medical, Vision, and Dental Insurance

401k Retirement Fund

Job summary

Creative Solutions Services, LLC seeks a mass spectrometry scientist (LC-MS) in Thousand Oaks, CA, for a 12-month contract. You will analyze proteins, peptides, and glycans, map modifications, and generate data with RPLC-MS and native-MS techniques to support early discovery and later-stage optimization.

The role requires 2+ years of biopharma analytical chemistry experience, strong MS data handling, and the ability to work independently to meet deadlines in a fast-paced environment.

Qualifications

• Doctorate or equivalent in analytical chemistry or biochemistry.
• Experience in biopharmaceutical analytical chemistry and protein analysis.
• Strong MS-based analytical skills and data interpretation.

Responsibilities

• Conduct protein, peptide, and glycan analysis and characterization using LC-MS techniques.
• Perform auto-digestion and peptide mapping and report findings to teams.
• Generate and communicate MS data to support early discovery and later-stage optimization.
• Work with intact and subunit protein mass analysis using RPLC-MS.
• Handle large LC-MS data sets and maintain accurate ELN records.
• Present results clearly and work independently to meet deadlines.
• Follow established protocols and maintain accurate lab notebook entries.

Skills

LC-MS analysis

Education

Doctorate

Master's degree + 2 years biopharmaceutical Analytical Chemistry

Bachelor's degree + 4 years biopharmaceutical Analytical Chemistry

Tools

MassHunter

XCalibur

MassLynx

ChemStation

Chromeleon

Job description

Scientist - LC-MS

Location: Thousand Oaks, CA

Onsite Flexibility: Onsite

Contract Details

• Position Type: Contract
• Contract Duration: 12 months
• Pay Rate: $38.00-$42.00 / Hour (USD)
• Work Authorization: Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Job Summary

This is an exciting opportunity for a mass spectrometry scientist and analytical protein chemist with a consistent track record in biopharmaceutical protein support, scientific eminence, and leadership and mentoring skills. You will be part of the BEAM group, providing scientific and technical expertise to support early discovery research through to later-stage molecule optimization and late-stage selection of the client's pipeline of drug candidates. This position is an exciting opportunity to unlock the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing, and delivering innovative human therapeutics.

Key Responsibilities

• Conduct protein, peptide, and glycan analysis and characterization using mass spectrometry techniques, including RPLC-MS, RPLC-MS/MS, native-MS, and other hyphenated MS analytical capabilities.
• Perform auto-digestion and/or peptide mapping.
• Generate reports and communicate the resulting data and associated reports to the project team to support the diverse early-stage pipeline.
• Experience using analytical characterization techniques such as RPLC-MS for intact protein, reduced, and subunit protein mass analysis.
• Experience generating, processing, and using large LC-MS analytical data sets.
• Communicate (verbal and in written) scientific concepts and results.
• Work independently in advancing projects and studies within required deadlines.
• Follow protocols and procedures, maintain accurate records in an electronic lab notebook.

Required Skills

• Liquid chromatography Mass Spectrometry (LC-MS), protease digestion, intact protein analysis, and peptide mapping.

Preferred Skills

• Experience using high-throughput MS like Rapidfire-MS.
• Experience with protein digestion and RPLC-MS/MS to map protein sequence and characterize post-translational modifications such as deamidation, isomerization, and oxidation, and associated data processing.
• Experience with both ESI and MALDI techniques.
• Knowledge of multiple mass spectrometric (MassHunter, XCalibur, MassLynx) and chromatographic (ChemStation, Chromeleon) control software. Knowledge of GeneData Expressionist data processing software is a plus.
• Knowledge of statistical processing of data, including related software such as, but not limited to, Excel, Spotfire, or JMP.
• Master's or PhD-level qualification with an emphasis in mass spectrometric analytical characterization.

Education Requirements

• Doctorate degree; OR
• Master's degree and 2 years of biopharmaceutical Analytical Chemistry, Biochemistry, or equivalent; OR
• Bachelor's degree and 4 years of biopharmaceutical Analytical Chemistry, Biochemistry, or equivalent.

Required Experience

• Minimum 2 years of experience in biopharmaceutical Analytical Chemistry, Biochemistry, or equivalent (with Master's degree); OR minimum 4 years with a Bachelor's degree.

Important Notes

• Interview Process: The hiring manager will review resumes first and conduct approximately 3-4 phone/Teams interviews for top candidates. Team members may then conduct Teams interviews (within 3-4 people) to choose the final candidate.

About GTT

GTT is a minority-owned staffing firm and a subsidiary of Chenega Corporation, a Native American-owned company in Alaska. We highly value diverse and inclusive workplaces and support Fortune 500 organizations across banking, financial services, technology, life sciences, biotech, utilities, and retail sectors throughout the U.S. and Canada.

Benefits

• Medical, Vision, and Dental Insurance Plans
• 401k Retirement Fund

Job Number: 26-13873

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