Scientist III # 26-23218

US Tech Solutions; Worcester (MA); On-site; USD 90,000 - 140,000; Full time

Job summary

US Tech Solutions is seeking a Scientist for our Bioresearch Center in Worcester, MA to join the Analytical Development team. You will develop and apply LC-MS and biophysical methods to characterize biologics across discovery to commercial stages.

The role emphasizes method development, data integrity, and collaboration with cross-functional teams in a fast-paced biotech environment. This 12‑month contract requires strong communication and lab skills.

Qualifications

• Bachelor's or Master's in chemistry, biology, biochemistry, or related field with typically 5+ (BS) or 2+ (MS) years of biotech/pharma experience.
• Hands‑on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis, and protein biophysical characterization.
• Knowledge of HPLC or AKTA instrumentation.
• Fundamental understanding of protein structure, post‑translational modifications, and analytical methods used for protein characterization.
• Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is desirable.
• Knowledge of vibrational spectroscopy (IR, NIR, Raman) and multivariate analysis is desirable.
• Proficient with Windows 10 and Microsoft Office.
• Excellent written and oral communication, organization, and multitasking skills.
• Understand and adhere to corporate standards regarding safety and handling of materials.

Responsibilities

• Perform mass spectrometry analyses of biologics to provide sequence verification and PTM profiles.
• Independently perform separation methods using HPLC and AKTA.
• Perform biophysical methods (DSC) to support characterization studies.
• Design and execute experiments for method development and investigations.
• Support process development by materials analysis and metabolomics experiments.
• Generate and communicate precise, reliable data in a timely manner.
• Organize and document experiments in ELN.
• Draft protocols and technical reports.
• Maintain lab equipment.

Skills

Mass spectrometry

LC-MS

Biophysical characterization

HPLC

AKTA

Protein structure & PTMs

Data organization

Communication skills

MS data analysis

Education

Bachelor's degree in chemistry/biochemistry/biology

Master's degree in chemistry/biochemistry/biology

Tools

HPLC

AKTA

LC-MS

DSC

Job description

Duration: 12 months contract

Job Description:

Client’s Bioresearch Center in Worcester, MA. The team is responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities from discovery through commercial stages. The Client is searching for a highly motivated Scientist to join their Analytical Development team at

As a Scientist, you will be a part of the Analytical Characterization Group (ACG) within the Analytical Development Department. ACG focuses on providing routine, investigative, and in-depth characterization analyses of Client’s biologics to support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC‑MS), spectroscopy and various other biophysical assays.

The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department.

Key Responsibilities:

• Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS) of Client’s biologics to provide sequence verification and post‑translational modification profiles.
• Independently perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA.
• Perform biophysical methods (e.g., DSC) of Client’s biologics to support characterization studies.
• Design and execute experiments for method development and/or investigations.
• Support process development by performing raw material analysis using vibrational spectroscopy and executing metabolomics experiments using mass spectrometry.
• Generate and communicate precise, reliable, and reproducible data in a timely manner.
• Organize and document experiments and results in an electronic laboratory notebook.
• Draft protocols, method development reports, and technical characterization reports.
• Maintain lab equipment.

Qualifications:

• Bachelors or Masters in chemistry, biology, biochemistry, or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting.
• Hands‑on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis, and protein biophysical characterization.
• Knowledge of HPLC or AKTA instrumentation.
• Fundamental understanding of protein structure, post‑translational modifications, and analytical methods used for protein characterization.
• Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is highly desirable.
• Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
• Proficient with Windows 10 and Microsoft Office (Outlook, Excel, Word, and PowerPoint).
• Excellent written communication, oral communication, organization, and multitasking skills.
• Hardworking and motivated to drive both efficiency and quality.
• Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials.