Scientist

Mindlance; Worcester (MA); On-site; USD 80,000 - 110,000; Full time

Job summary

Mindlance in Worcester, MA is seeking a contract Scientist II for the Cell and Functional Biology team within Biotherapeutics Discovery to perform high-throughput antibody binding and functional screening for data-driven project decisions.

You will execute ELISA, flow cytometry, and cell-based assays, optimize screening workflows, maintain mammalian cell culture lines, analyze data, and help standardize and automate current protocols to enable efficient discovery efforts.

Qualifications

• Bachelor’s or Master’s degree with relevant biotech/pharma experience
• Hands-on flow cytometry assay execution and troubleshooting
• Experience with high-throughput screening workflows
• Familiarity with protein-protein interaction assays and ELISA
• Experience maintaining immortalized mammalian cell culture
• Experience with functional cellular assays
• Strong cross-functional communication skills

Responsibilities

• Perform high-throughput antibody screening workflows using flow cytometry and reporter assays
• Evaluate antibody binding, potency, and selectivity via ELISA and flow cytometry
• Coordinate sourcing of reagents for screening assays
• Develop and standardize screening workflows and automation procedures
• Maintain immortalized mammalian cell lines

Skills

Flow cytometry

High-throughput screening

Data analysis

Cross-functional teamwork

Education

Bachelor’s Degree or equivalent

Master’s Degree or equivalent

Tools

Automated liquid handling systems

Mammalian cell culture

Immunoassays (ELISA)

Job description

Location/Site: ABC, Worcester, MA – 100% onsite

Number of Interviews : 4 (30 min each)

Job Description:

The Cell and Functional Biology team within Biotherapeutics Discovery is seeking a contract Scientist II to perform high-throughput antibody binding and functional screening to enable data-driven decisions on project advancement. This individual will execute, optimize, and analyze ELISA, flow cytometry, and cell-based assays as part of antibody discovery. The role includes optimizing and executing antibody screening, maintaining mammalian cell culture lines, analyzing data and standardizing and automating current protocols.

Key Responsibilities Include:

• Perform high-throughput antibody screening workflows, including flow cytometry-based binding, internalization, and reporter assays using automated liquid-handling systems.
• Perform and analyze experiments to evaluate antibody binding, potency, and selectivity using immunoassay platforms, including ELISA and flow cytometry.
• Coordinate sourcing of internal and commercial reagents for screening assays
• Develop and standardize screening workflows, assay protocols, and automation procedures.
• Maintain immortalized mammalian cell lines

Qualifications

• Bachelor’s Degree or equivalent education with typically approximately 5 years of relevant biotech or pharmaceutical industry experience, or Master’s Degree or equivalent education with typically two years of experience
• Strong hands-on experience with flow cytometry assay execution and troubleshooting
• Strong experience with high-throughput screening workflows
• Familiarity with protein-protein interaction assays, ELISA experience preferred
• Familiarity with immortalized mammalian cell culture
• Prior experience with functional cellular assays
• Excellent communication skills and demonstrated ability to work effectively in cross-functional teams.

EEO: “Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.”