Bench Scientist

Mindlance; Andover (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

A leading recruiting company is seeking a Bioanalytical Scientist to work in a state-of-the-art laboratory focused on developing sensitive quantitative assays. This role requires a BS/MS in biochemistry, biology, or chemistry and 3-5 years of experience, preferably in the biopharma sector. The candidate must have strong expertise in mass spectrometry and method development, plus excellent collaboration and data analysis skills. This is an on-site position offering a unique opportunity to contribute to biotherapeutic research.

Qualifications

• 3-5 years of experience in bioanalytical or biopharma field.
• Expertise in mass spectrometry operations and maintenance.
• Strong collaborative and independent working skills.

Responsibilities

• Apply protein quantitation workflows using immunoaffinity enrichment.
• Run bioanalytical assays independently.
• Operate and maintain chromatography and mass spectrometry instrumentation.
• Analyze quantitative LC-MS/MS data.

Skills

Bioanalytical procedures

Protein biochemistry

Method development

Data analysis

Mass spectrometry

Education

BS/MS in biochemistry, biology or chemistry

Advanced degree

Tools

Nanospray triple quadrupole mass spectrometer

Liquid chromatography

Job description

Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at http://www.mindlance.com.

Job Description

Top 3 critical skills:

Years of experience are required: 3-5 year

Minimum education experience required: BS/MS level education in biochemistry, biology or chemistry or related fields required; advanced degree may be a plus.

Job Description:

A rare position is available for a bioanalytical scientist to join a state‑of‑the‑art protein mass spectrometry laboratory in ompany's Pharmacokinetics Dynamics and Metabolism department. The lab-based role will focus on the development of a novel type of sensitive quantitative assay to characterize and quantify the effect of anti-drug antibodies against protein biotherapeutics in the context of unwanted immunogenicity. This position requires expertise in bioanalytical procedures including immunoanalytical workflows, solid background in protein biochemistry, and ideally expertise in triple quadrupole quantitative mass spectrometry. The candidate will participate in all phases of mass spectrometry laboratory operations including the development of sample preparation methods, assay execution, instrument maintenance and data analysis/reporting. We are looking for a scientist passionate about learning and quickly applying new skills to the project needs.

Responsibilities

• Apply existing protein quantitation workflows using bead and column based immunoaffinity enrichment including the use of liquid handling robotics.
• Run bioanalytical assays under minimal supervision; initiative in method development is expected.
• Independent daily operation, calibration, maintenance, and troubleshooting of multi-dimensional nanoflow liquid chromatography and nanospray triple quadrupole mass spectrometry instrumentation.
• Support analysis of quantitative LC-MS/MS data using relevant bioinformatics and quantitation software.

Qualifications, Technical Skills and Experience

• BS/MS level education in biochemistry, biology or chemistry or related fields required; advanced degree may be a plus.
• Industry experience in biopharma preferred.
• Expertise in the operation and maintenance of mass spectrometers, ideally with quantitative protein LC-MS/MS assays.
• Track record of method development skills particularly with novel and complex methods applied to bioanalytical questions.
• Work well both independently and as part of a team. Collaborative skills and effective partnering skills in a matrix-environment.
• Strong data organization and analysis skills.

Additional Skills

• Industry experience in biopharma preferred.
• Expertise in the operation and maintenance of mass spectrometers, ideally with quantitative protein LC-MS/MS assays.
• Track record of method development skills particularly with novel and complex methods applied to bioanalytical questions.
• Work well both independently and as part of a team. Collaborative skills and effective partnering skills in a matrix-environment.
• Strong data organization and analysis skills.