Research Associate-Burclaff Lab

North Carolina State University; Raleigh (NC); On-site; USD 60,000 - 70,000; Full time

Benefits offered by this job

Medical, Dental, and Vision

Retirement Programs

Paid Time Off

Job summary

North Carolina State University in Raleigh seeks a Research Associate for the Burclaff Lab to advance metabolism and stem cell biology studies. You will manage primary cell cultures, conduct molecular assays, and support in vivo mouse work while ensuring rigorous laboratory operations.

The role requires a relevant post-Baccalaureate degree or equivalent, with experience in mammalian cell culture and molecular techniques. A collaborative environment and strong data management are emphasized.

Qualifications

• Experience in mammalian primary cell culture (establishment and maintenance).
• Experience in molecular biology and biochemistry techniques (PCR; RT-qPCR; gel electrophoresis; DNA, RNA, and protein extraction; immunofluorescence; immunohistochemistry).
• Experience in mouse colony management and in vivo experimentation.

Responsibilities

• Primary Cell Culture Management: establish, propagate, and maintain mammalian cultures using aseptic techniques for projects.
• Molecular & Biochemical Assays: perform DNA/RNA/protein extraction, PCR/RT-qPCR, gel electrophoresis, and related analyses.
• Animal Model Care & In Vivo Research: manage mouse colonies, handling, breeding, genotyping, tissue collection, and procedures per guidelines.
• Laboratory Operations & Instrumentation: maintain and troubleshoot equipment, manage inventory and data logs, follow safety SOPs.

Skills

Mammalian cell culture

Molecular biology

Biochemistry

Computer literacy

Education

Post-Baccalaureate degree / Bachelor's + 3+ years

Tools

PCR / RT-qPCR

Gel electrophoresis

Immunofluorescence / IHC

Job description

Position

Research Associate-Burclaff Lab

Anticipated Hiring Range: Commensurate with education and experience ($60,000 - $70,000)

Work Schedule: Monday- Friday 8:00 a.m.- 5:00 p.m. with occasional overtime.

Job Location: Raleigh, NC

Department: Department of Molecular Biomedical Sciences

About the Department

North Carolina State University's College of Veterinary Medicine (NC State CVM) is a dynamic community whose members are dedicated to preparing veterinarians, veterinarian scientists, and biomedical scientists while advancing animal and human health from the cellular level through entire ecosystems.

The Department of Molecular Biomedical Sciences at the NC State CVM trains veterinarians, graduate students, and postdoctoral fellows in research-based careers focused on discovering new information about animal and human health and disease and using those findings to enhance animal and human health and wellbeing.

Benefits

• Medical, Dental, and Vision
• Flexible Spending Account
• Retirement Programs
• Disability Plans
• Life Insurance
• Accident Plan
• Paid Time Off and Other Leave Programs
• 12 Holidays Each Year
• Tuition and Academic Assistance
• And so much more!

Attain Work-life balance with our Childcare benefits, Wellness & Recreation Membership, and Wellness Programs that aim to build a thriving wolfpack community.

Disclaimer: Perks and Benefit eligibility is based on Part-Time or Full-Time Employment status. Eligibility and Employer Sponsored Plans can be found within each of the links offered.

Duties and Responsibilities

The Burclaff Lab focuses on understanding how metabolism and cellular energetics are regulated within intestinal stem cells, and how this dynamic regulation supports homeostasis, identity maintenance, fate decisions, cell cycle regulation, and tissue plasticity following injury or disease. We utilize a mix of animal models and cutting-edge, genetically modified, primary human intestinal stem cell cultures to advance our understanding of the mammalian intestine.

The Research Associate will advance research operations, understand project rationales, and execute experiments to test scientific hypotheses across mouse models, cell lines, and primary cell cultures. In this role, you will also assist with laboratory management, including inventory tracking, equipment oversight, and day-to-day operational organization.

• Primary Cell Culture Management: Establish, propagate, and maintain mammalian primary cell cultures and established cell lines using aseptic techniques to support research projects.
• Molecular & Biochemical Assays: Perform routine and advanced molecular biology and biochemical assays, including DNA/RNA protein extraction, PCR, RT-qPCR, gel electrophoresis, tissue sectioning, immunofluorescence, immunohistochemistry staining, and live image analysis.
• Animal Model Care & In Vivo Research: Oversee mouse colony operations-including handling, breeding, weaning, genotyping, and tissue collection-and execute experimental procedures in accordance with institutional guidelines.
• Laboratory Operations & Instrumentation: Maintain, calibrate, and troubleshoot laboratory equipment, manage inventory and data logs, and ensure strict compliance with safety protocols and standard operating procedures.

If you are a collaborative scientist who enjoys hands-on research, solving problems, and keeping complex laboratory operations running smoothly, we encourage you to apply.

Other Responsibilities

Additional duties include organizing and maintaining research data, drafting or editing documents, contributing to publications, grant applications, and presentations.

Qualifications

Relevant post-Baccalaureate degree, or relevant Bachelor's degree plus 3 or more years of independent research experience. May require terminal degree and licensure. All degrees must be received from appropriately accredited institutions.

• Experience in mammalian primary cell culture (establishment and maintenance)
• Experience in molecular biology and biochemistry techniques (PCR; RT-qPCR; gel electrophoresis, DNA, RNA, and protein extraction; immunofluorescence; immunohistochemistry)
• Experience in mouse colony management (animal handling, breeding, weaning, genotyping, etc) and in vivo experimentation

• Prior research experience.
• Ability to work with animals.
• Strong computer skills and ability to use highly specialized laboratory equipment with troubleshooting abilities.

N/A

No

No

Recruitment Dates

Job Open Date: 08/28/2026

Anticipated Close Date: 9/14/2026; if posting is still active we are accepting and reviewing applications.

EEO & Background Checks

NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.

If you have general questions about the application process, you may contact Human Resources at [phone] or [e-mail].

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.