Research Associate, Antibody Discovery

BioSpace; San Diego (CA); On-site; USD 68,000 - 83,000; Full time

Job summary

AlivaMab Biologics is seeking a Research Associate to join the Antibody Discovery Team in San Diego, supporting discovery and screening workflows on the AlivaMab Mouse platform. You will contribute to antibody discovery and collaborate with cross-functional teams in Antibody Discovery, Antibody Engineering, and Protein Sciences.

Responsibilities include animal work, cell culture, ELISA/flow cytometry, high-throughput screening, and meticulous record-keeping.

Qualifications

• BS or MS in immunology, cell biology, or related discipline with 0-3 years of relevant industrial or academic experience.
• Small-animal work, including immunization, blood collection, and tissue harvest performed in accordance with IACUC guidelines, is an integral part of this role. Prior hands-on experience with these procedures is an advantage.
• Aseptic mammalian tissue culture experience is required. Demonstrated expertise in culturing cancer cell lines and hybridomas is preferred.
• Ability to work efficiently, both independently and as part of a team, on challenging drug discovery projects that use high-throughput cell culture and antibody screening techniques.
• Proficiency in Microsoft Office (Word, Excel, PowerPoint) and GraphPad Prism. Experience with Benchling ELN/LIMS is a plus.
• The successful candidate will be self-motivated, detail-oriented, and eager to learn and develop new skills and techniques in antibody drug discovery.
• Experience with stable cell line generation, cell sorting, and/or experimental design of cell-based assays is desired.
• Strong analytical, troubleshooting, and communication skills with meticulous attention to detail
• Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
• Local candidate preferred. No relocation assistance is offered for this position.

Responsibilities

• Perform mouse immunizations, sera titer assessment, and tissue collection
• Maintain mammalian cell lines for cell-based assays across multiple projects
• Screen antibodies using ELISA, flow cytometry, and cell-based functional assays
• Prepare reagents and maintain an up-to-date inventory, including monitoring stock levels and reordering as needed
• Demonstrate initiative and creativity in experimental design, execution, and troubleshooting
• Execute high-throughput processes to support antibody discovery and screening workflows using automation
• Effectively maintain meticulous records of lab activities using an electronic notebook (Benchling); communicate findings clearly through written reports and presentations to support project progression and scientific decision-making
• Contribute innovative ideas and collaborate effectively across teams to drive research excellence and project success in a fast-paced environment

Skills

Immunology knowledge

Cell culture techniques

Team collaboration

Documentation/reporting

High-throughput screening

Education

BS/MS in immunology or related field

Tools

Benchling ELN/LIMS

GraphPad Prism

Job description

Overview

AlivaMab Biologics is seeking an outstanding individual to join the Antibody Discovery Team. The successful candidate will serve as the Research Associate, supporting antibody discovery and screening workflows, enabling identification of antibody hits with therapeutic potential from the AlivaMab® Mouse platform, and contributing to broader technology development and companywide initiatives in collaboration with cross-functional scientific teams, working closely with scientists in Antibody Discovery, Antibody Engineering, and Protein Sciences teams. The successful candidate will be a highly motivated team player and able to multitask in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs.

Responsibilities

• Perform mouse immunizations, sera titer assessment, and tissue collection
• Maintain mammalian cell lines for cell-based assays across multiple projects
• Screen antibodies using ELISA, flow cytometry, and cell-based functional assays
• Prepare reagents and maintain an up-to-date inventory, including monitoring stock levels and reordering as needed
• Demonstrate initiative and creativity in experimental design, execution, and troubleshooting
• Execute high-throughput processes to support antibody discovery and screening workflows using automation
• Effectively maintain meticulous records of lab activities using an electronic notebook (Benchling); communicate findings clearly through written reports and presentations to support project progression and scientific decision-making
• Contribute innovative ideas and collaborate effectively across teams to drive research excellence and project success in a fast-paced environment

Qualifications

• BS or MS in immunology, cell biology, or related discipline with 0-3 years of relevant industrial or academic experience.
• Small-animal work, including immunization, blood collection, and tissue harvest performed in accordance with IACUC guidelines, is an integral part of this role. Prior hands-on experience with these procedures is an advantage.
• Aseptic mammalian tissue culture experience is required. Demonstrated expertise in culturing cancer cell lines and hybridomas is preferred.
• Ability to work efficiently, both independently and as part of a team, on challenging drug discovery projects that use high-throughput cell culture and antibody screening techniques.
• Proficiency in Microsoft Office (Word, Excel, PowerPoint) and GraphPad Prism. Experience with Benchling ELN/LIMS is a plus.
• The successful candidate will be self-motivated, detail-oriented, and eager to learn and develop new skills and techniques in antibody drug discovery.
• Experience with stable cell line generation, cell sorting, and/or experimental design of cell-based assays is desired.
• Strong analytical, troubleshooting, and communication skills with meticulous attention to detail
• Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
• Local candidate preferred. No relocation assistance is offered for this position.

About AlivaMab Biologics

AlivaMab Biologics sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers fully human antibodies on exceptional timelines. AMB achieves its partners’ design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on the rapid and efficient delivery of antibodies, characterized for function, kinetics, and developability, and on engineering alternative formats, including multispecifics and CARs. The AMB team’s experience and passion for antibody drug discovery and development, combined with trusted, proven technologies, including Ablexis’ AlivaMab® Mouse platforms, ensure the highest probability of success.

AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion or creed, sex, sexual orientation, gender, gender identity or expression, pregnancy, childbirth or related medical conditions, reproductive health decision-making, national origin, ancestry, age, physical or mental disability, medical condition, genetic information, marital status, citizenship or immigration status, veteran or military status, or any other characteristic protected by applicable federal, state, or local law.

Salary Range: $67,500 - $82,500 annually

This range represents AlivaMab Biologics’ good-faith estimate of the base compensation for this position at the time of posting. Offered compensation will account for factors such as experience, education, and comprehensiveness of qualifications. The salary range excludes bonuses, equity, health benefits, PTO, other benefits, or any other forms of compensation that may be part of the total compensation package.