Senior Research Associate – Mouse Immunization for Antibody Discovery

Kisoji Biotechnology Inc.; San Diego (CA); On-site; USD 90,000 - 120,000; Full time

Benefits offered by this job

Comprehensive Health / Dental Insurance Plans

Paid Vacation and Company Holidays

Training and Professional Development Opportunities

Job summary

Kisoji Biotechnology Inc. is seeking a Senior Research Associate to join their therapeutic antibody discovery program in San Diego, California. This role involves managing mouse colonies and executing immunization strategies to generate antibodies against novel therapeutic targets.

The ideal candidate will have a strong background in immunology or a related field, with proficiency in rodent handling and in vivo techniques. The position offers a benefits package including health insurance and professional development opportunities.

Qualifications

• 3 to 5 years of experience in a biotech or pharmaceutical R&D environment.
• Experience in blood and tissue collection and multiple injection routes.
• Hands-on experience in transgenic mouse colony management, breeding, and genotyping.

Responsibilities

• Assist in designing immunization strategies based on target biology.
• Conduct routine immunization procedures in small rodents and monitor health.
• Maintain and expand the company's mouse colonies and manage laboratory operations.

Skills

Rodent handling

In vivo techniques

Mouse colony management

Cell culture

Attention to detail

Communication skills

Education

M.S. or B.S. in Immunology, Cell Biology, Biology or related

Job description

therapeutics for cancer and other diseases. Our proprietary platform combines multi-species single-domain antibody transgenic mice, AI-enabled antibody discovery, and multispecific antibody engineering to create highly differentiated and manufacturable therapies.

We are currently seeking a self-motivated Senior Research Associate to join the mouse immunization team for our therapeutic antibody discovery program. The successful candidate will play a crucial role in the early stages of antibody drug discovery, specializing in mouse colony management and executing mouse immunization strategies to generate antibodies against novel therapeutic targets.

Key Responsibilities

• Immunization strategy development: Assist in designing immunization strategies based on target biology, antigen format, and project goals. Design and optimization of mouse immunization protocols, including adjuvant selection and in vivo immunization procedures, to generate robust immune responses against complex targets.
• Conduct routine immunization procedures in small rodents with high efficiency: Prepare antigens and adjuvants; conduct animal handling and various injection routes (SC, ID, IM, IP, IV); monitor animal health and immune responses in accordance with established protocols and ethical guidelines; collect blood samples via multiple routes; harvest lymphoid tissues (spleen, lymph nodes, and other lymphoid organs); and isolate immune cells using sterile and aseptic techniques. Coordinate shipment of biological samples to internal company sites when required.
• Mouse colony management: Work with the team members and vivarium staff to maintain and expand the company's mouse colonies, including breeding strategy design, colony management, genotyping, and data tracking and documentation.
• Laboratory maintenance: Maintain accurate experimental records and ensure data integrity. Manage laboratory inventory, equipment, and daily operations. Ensure all procedures comply with SOPs and institutional safety and animal care regulations.

Qualifications

• M.S. or B.S. in Immunology, Cell Biology, Biology, or a related discipline, with at least 3 to 5 years of experience in a biotech or pharmaceutical R&D environment.
• Strong proficiency in rodent handling and in vivo techniques, particularly blood and tissue collection and multiple injection routes. Hands‑on experience in transgenic mouse colony management, breeding, and genotyping.
• Hands‑on experience with cell culture and primary cell isolation from rodent tissues.
• Highly detail‑oriented with a strong ability to generate accurate, reliable, and reproducible experimental results.
• Strong team player with excellent written and verbal communication skills, as well as strong documentation and organizational abilities.

What We Offer

Benefits Package Includes

• Comprehensive Health / Dental Insurance Plans
• Paid Vacation and Company Holidays

Incentive Programs Include

• Training and Professional Development Opportunities
• Annual Performance Reviews with Performance‑Based Bonus Eligibility

Salary

The salary range for this position is $90,000–$120,000 USD. Compensation will be determined based on factors including relevant experience, skills, education, training, and internal equity.