Antibody Discovery Research Associate — Hands-on

BioSpace; San Diego (CA); On-site; USD 68,000 - 83,000; Full time

Job summary

AlivaMab Biologics is seeking a Research Associate to join the Antibody Discovery Team in San Diego, supporting discovery and screening workflows on the AlivaMab Mouse platform. You will contribute to antibody discovery and collaborate with cross-functional teams in Antibody Discovery, Antibody Engineering, and Protein Sciences.

Responsibilities include animal work, cell culture, ELISA/flow cytometry, high-throughput screening, and meticulous record-keeping.

Qualifications

• BS or MS in immunology, cell biology, or related discipline with 0-3 years of relevant industrial or academic experience.
• Small-animal work, including immunization, blood collection, and tissue harvest performed in accordance with IACUC guidelines, is an integral part of this role. Prior hands-on experience with these procedures is an advantage.
• Aseptic mammalian tissue culture experience is required. Demonstrated expertise in culturing cancer cell lines and hybridomas is preferred.
• Ability to work efficiently, both independently and as part of a team, on challenging drug discovery projects that use high-throughput cell culture and antibody screening techniques.
• Proficiency in Microsoft Office (Word, Excel, PowerPoint) and GraphPad Prism. Experience with Benchling ELN/LIMS is a plus.
• The successful candidate will be self-motivated, detail-oriented, and eager to learn and develop new skills and techniques in antibody drug discovery.
• Experience with stable cell line generation, cell sorting, and/or experimental design of cell-based assays is desired.
• Strong analytical, troubleshooting, and communication skills with meticulous attention to detail
• Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
• Local candidate preferred. No relocation assistance is offered for this position.

Responsibilities

• Perform mouse immunizations, sera titer assessment, and tissue collection
• Maintain mammalian cell lines for cell-based assays across multiple projects
• Screen antibodies using ELISA, flow cytometry, and cell-based functional assays
• Prepare reagents and maintain an up-to-date inventory, including monitoring stock levels and reordering as needed
• Demonstrate initiative and creativity in experimental design, execution, and troubleshooting
• Execute high-throughput processes to support antibody discovery and screening workflows using automation
• Effectively maintain meticulous records of lab activities using an electronic notebook (Benchling); communicate findings clearly through written reports and presentations to support project progression and scientific decision-making
• Contribute innovative ideas and collaborate effectively across teams to drive research excellence and project success in a fast-paced environment

Skills

Immunology knowledge

Cell culture techniques

Team collaboration

Documentation/reporting

High-throughput screening

Education

BS/MS in immunology or related field

Tools

Benchling ELN/LIMS

GraphPad Prism

Job description

AlivaMab Biologics is seeking a Research Associate to join the Antibody Discovery Team in San Diego, supporting discovery and screening workflows on the AlivaMab Mouse platform. You will contribute to antibody discovery and collaborate with cross-functional teams in Antibody Discovery, Antibody Engineering, and Protein Sciences.

Responsibilities include animal work, cell culture, ELISA/flow cytometry, high-throughput screening, and meticulous record-keeping.