Remote Senior Principal Statistical Programmer (SAS/CDISC)

WCG Clinical, Inc.; Columbus (OH); Remote; USD 131,000 - 160,000; Full time

Benefits offered by this job

Health insurance

401(k) match

Tuition reimbursement

Career development

Paid time off

Job summary

WCG Clinical, Inc. seeks a Senior Principal Statistical Programmer to lead complex programming in clinical trials, providing expert SAS and R analysis and ensuring regulatory deliverables meet CDISC standards.

This remote, senior‑level role offers mentorship and cross‑functional collaboration with biostatistics, data management, and IT to drive automation, standardization, and efficient programming outputs.

Qualifications

• Minimum 8–10 years of statistical programming experience in a clinical trial environment.
• Deep expertise in SAS programming, including complex analyses and regulatory deliverables.
• Proficiency in R programming is a must.
• Demonstrated experience with CDISC standards and regulatory requirements.
• Proven ability to independently lead complex programming efforts across studies.
• Experience mentoring staff and driving technical standards or best practices.
• Demonstrated ability to independently coordinate biostatistical projects, including planning and oversight of programming activities, with minimal direction from senior leadership.

Responsibilities

• Lead complex programming across multiple studies or functional areas.
• Design, develop, validate, and oversee complex programming deliverables (datasets, tables, listings, figures).
• Lead development, validation, and improvement of DMC macros and programming standards.
• Provide technical oversight and review of programming work for quality and compliance.
• Drive programming standards and process improvements.
• Collaborate with biostatistics and study teams on trial designs and DMC reporting.
• Mentor and lead statistical programming staff to develop skills and best practices.
• Support proposals, project planning, and scope discussions as needed.
• Partner with IT to support SAS environments and system validation.
• Ensure deliverables align with regulatory submissions and CDISC standards.

Skills

SAS programming

R programming

Project leadership

Mentoring staff

CDISC standards

Education

Master’s degree

Tools

SAS Environments

System Validation Tools

Job description

WCG Clinical, Inc. seeks a Senior Principal Statistical Programmer to lead complex programming in clinical trials, providing expert SAS and R analysis and ensuring regulatory deliverables meet CDISC standards.

This remote, senior‑level role offers mentorship and cross‑functional collaboration with biostatistics, data management, and IT to drive automation, standardization, and efficient programming outputs.