Remote Senior Early-Phase Clinical Project Manager

Syneos Health, Inc.; North Carolina; Remote; USD 120,000 - 180,000; Full time

Job summary

Syneos Health in the United States is seeking a Sr Clinical Project Manager for Early Phase to lead Phase I trials from startup to closeout. You will serve as the primary sponsor liaison, manage timelines, budgets, and cross-functional teams to ensure study delivery in compliance with GCP/ICH and company SOPs.

The role requires strong leadership, excellent communication, and the ability to navigate complex regulatory environments, ensuring TMF quality and audit readiness across studies.

Qualifications

• Bachelor's degree in Life Sciences or related field.
• 5+ years of clinical research with progressive project management responsibilities.
• Experience managing Phase I and/or early-phase clinical trials.
• Strong knowledge of GCP, ICH guidelines, and global regulatory requirements.
• Proficiency with CTMS, eTMF, and related clinical trial technologies.

Responsibilities

• Lead all aspects of assigned early-phase clinical trials from study startup through database lock and closeout.
• Serve as the primary liaison between sponsors, internal teams, vendors, and study sites.
• Develop and manage project timelines, milestones, resources, risks, finances, and deliverables.
• Ensure projects are executed according to protocols, budgets, and regulatory requirements.
• Lead cross-functional teams to achieve study goals while maintaining quality, timelines, and budget expectations.

Skills

Project leadership

Sponsor liaison

Stakeholder management

CTMS/eTMF knowledge

Budget oversight

Communication skills

Education

Bachelor's degree in Life Sciences or related

Tools

CTMS

eTMF

Job description

Syneos Health in the United States is seeking a Sr Clinical Project Manager for Early Phase to lead Phase I trials from startup to closeout. You will serve as the primary sponsor liaison, manage timelines, budgets, and cross-functional teams to ensure study delivery in compliance with GCP/ICH and company SOPs.

The role requires strong leadership, excellent communication, and the ability to navigate complex regulatory environments, ensuring TMF quality and audit readiness across studies.