Principal Scientist, Thymic Regeneration & Immune Rejuvenation

BioSpace

Englewood (NJ)

On-site

USD 160,000 - 215,000

Full time

2 days ago

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Job summary

BioSpace in the United States is seeking a Principal Scientist to lead the Thymic Regeneration Team, restoring thymic function and rejuvenating adaptive immunity.

You will develop iPSC-derived thymic epithelial cells (iTECs) and thymic organoids, and design directed-differentiation protocols to generate functional TECs from human iPSCs. The role requires a PhD or MD/PhD with 10+ years of relevant research experience in thymic biology and regenerative immunology.

Qualifications

PhD or MD/PhD required.
10+ years of research experience in thymic biology, stem cell differentiation, organoid engineering or regenerative immunology.
Deep knowledge of thymic epithelial cell biology, iPSC differentiation, T-cell development and tissue engineering.
Expert knowledge in experimental therapeutics and regenerative immune pipelines.

Responsibilities

Lead a team developing iPSC-derived thymic epithelial cells and thymic organoids.
Develop thymic regeneration concepts for immune reconstitution and rejuvenative medicine.
Design protocols to generate TECs from human iPSCs.
Collaborate with ICR scientists to advance immune rejuvenation.

Skills

Immunology

Thymic biology

iPSC differentiation

Organoid engineering

Experimental therapeutics

Translational research

Education

PhD or MD/PhD

Tools

iPSC culture

3D organoid culture

CRISPR gene editing

RNA-seq

Flow cytometry

Immunofluorescent microscopy

Job description

BioSpace in the United States is seeking a Principal Scientist to lead the Thymic Regeneration Team, restoring thymic function and rejuvenating adaptive immunity.

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