Principal Research Scientist – siRNA Platform Automation

AbbVie Inc.; Worcester (MA); On-site; USD 180,000 - 280,000; Full time

Benefits offered by this job

paid time off

medical/dental/vision insurance

401(k) to eligible employees

incentive programs

Job summary

AbbVie Inc. is seeking a Principal Research Scientist to establish a high-throughput siRNA screening platform and guide cross-functional teams. You will mentor scientists, design and interpret screening experiments, and drive siRNA optimization across programs.

The role emphasizes leadership, advanced molecular biology techniques, and collaboration with genetic medicine teams to advance therapeutic leads.

Qualifications

• Degree in molecular biology, biochemistry, chemical biology, or related field.
• Extensive experience in siRNA design and screening.
• Proven ability to lead optimization programs and collaborate with teams.

Responsibilities

• Establish high-throughput siRNA screening platform.
• Mentor scientists and lead siRNA optimization efforts.
• Design experiments and interpret screening data.
• Collaborate with cross-functional teams to advance programs.
• Provide day-to-day leadership to a small team.

Skills

siRNA design

in vitro screening

high-throughput assays

qRT-PCR

ELISA

flow cytometry

cell culture

leadership

data interpretation

Education

BS/MS/PhD in molecular biology/biochemistry/chemical biology

Tools

Hamilton automation

Tecan automation

Job description

AbbVie Inc. is seeking a Principal Research Scientist to establish a high-throughput siRNA screening platform and guide cross-functional teams. You will mentor scientists, design and interpret screening experiments, and drive siRNA optimization across programs.

The role emphasizes leadership, advanced molecular biology techniques, and collaboration with genetic medicine teams to advance therapeutic leads.