Senior Scientist: siRNA Therapeutics & Ex-Hepatic Delivery

AbbVie

Cambridge (MA)

On-site

USD 120,000 - 170,000

Full time

19 hours ago
Be an early applicant
Application generator

An application made for this job — a tailored resume and cover letter that speak straight to the posting.

Get past ATS filters

Job summary

AbbVie in Cambridge, MA is seeking a Senior Scientist I/II to join the siRNA group in Biotherapeutics and Genetic Medicine. You will design and execute experiments to advance RNA-based therapies and enable siRNA delivery for ex-hepatic pipelines, collaborating across functions to accelerate programs.

The role requires strong molecular biology expertise, in vitro/in vivo assays, and a track record of delivering high-quality results.

Qualifications

  • PhD/MS/BS with extensive experience in designing and executing in vitro and in vivo studies of siRNA delivery platforms.

Responsibilities

  • Lead cross-functional efforts to advance ex-hepatic siRNA therapeutics development.
  • Design and evaluate ex-hepatic siRNA delivery platforms for targeted tissues.
  • Conceive and execute proof-of-concept experiments to validate hypotheses.
  • Develop in vitro, ex vivo, and in vivo assays for siRNA candidates.
  • Work independently with high productivity and scientific rigor.
  • Interpret multidisciplinary data to guide future experiments.
  • Acquire deep knowledge of RNA biology and siRNA therapeutics.
  • Communicate results with stakeholders and cross-functional teams.
  • Contribute to publications and patent applications as needed.
  • Mentor junior scientists within the team.

Skills

siRNA delivery
Molecular biology
In vivo studies
RT-qPCR
RNA biology
Data analysis
Scientific communication

Education

PhD in Molecular Biology
MS in Biology
BS in Biomed/related

Tools

ELISA
Western Blot
ddPCR
NGS
Flow Cytometry
JESS

Job description

AbbVie in Cambridge, MA is seeking a Senior Scientist I/II to join the siRNA group in Biotherapeutics and Genetic Medicine. You will design and execute experiments to advance RNA-based therapies and enable siRNA delivery for ex-hepatic pipelines, collaborating across functions to accelerate programs.

The role requires strong molecular biology expertise, in vitro/in vivo assays, and a track record of delivering high-quality results.

Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Senior Scientist - siRNA Therapeutics & Ex-Hepatic Delivery
Senior Scientist - siRNA Therapeutics & Ex-Hepatic Delivery

ABBVIE • Cambridge (MA)

On-site
USD 110,000 - 209,000
Senior Scientist, siRNA Therapeutics & Delivery
Senior Scientist, siRNA Therapeutics & Delivery

AbbVie Inc. • Cambridge (MA), Northern (KY)

Hybrid
USD 120,000 - 190,000
Comprehensive benefits
Bonus program
Equity incentives
Senior Scientist, siRNA Therapeutics & Delivery
Senior Scientist, siRNA Therapeutics & Delivery

AbbVie Inc. • Cambridge (MA), Northern (KY)

Hybrid
USD 120,000 - 190,000
Comprehensive benefits
Bonus program
Equity incentives
Senior Scientist - siRNA Design & Off-Target Analysis
Senior Scientist - siRNA Design & Off-Target Analysis

AbbVie • Worcester (MA)

On-site
USD 120,000 - 170,000
Paid time off
Medical/dental/vision insurance
401(k) plan
+1
Director, siRNA Discovery & Portfolio Strategy
Director, siRNA Discovery & Portfolio Strategy

BioSpace • Cambridge (MA)

On-site
USD 260,000 - 380,000
Long-term incentive programs
Comprehensive benefits package
Paid time off
Senior Scientist, siRNA Therapeutics & Delivery
Senior Scientist, siRNA Therapeutics & Delivery

AbbVie • Cambridge (MA)

On-site
USD 120,000 - 170,000
Senior Scientist, siRNA Therapeutics & Delivery
Senior Scientist, siRNA Therapeutics & Delivery

ABBVIE • Cambridge (MA)

On-site
USD 110,000 - 209,000
Director, siRNA Discovery & Strategy
Director, siRNA Discovery & Strategy

AbbVie • Cambridge (MA)

On-site
USD 161,000 - 305,000
Senior Scientist II - RNA & Lipid NP Analytics
Senior Scientist II - RNA & Lipid NP Analytics

AbbVie • San Diego (CA)

On-site
USD 120,000 - 150,000
Medical/dental/vision insurance
401(k) plan
Senior Scientist II, mRNA & Lipid Nanoparticle Analytics
Senior Scientist II, mRNA & Lipid Nanoparticle Analytics

AbbVie Inc. • San Diego (CA)

On-site
USD 120,000 - 180,000
Healthcare benefits
401(k) plan
Paid time off