Onsite IT Support Specialist — Part-Time to Full-Time

JLSa2 Therapeutics; South San Francisco (CA); On-site; USD 52,000 - 83,000; Part time

Job summary

JLSa2 Therapeutics is seeking a hands-on IT professional to support our growing team in a startup environment. The role starts as part-time onsite (≈20 hours/week, 9am-1pm or 10am-2:30pm) and will transition to full-time as the company scales.

You will handle day-to-day IT support, workstation setup, AD/Entra ID, Microsoft 365, and network infrastructure, with responsibilities expanding as we grow. The ideal candidate is highly organized, an independent self-starter, and a team player in a

Qualifications

• 4 year degree in relevant coursework.
• 3+ years of IT support experience across help desk and systems administration.
• Solid knowledge of Windows and macOS, Active Directory or Entra ID, and cloud productivity platforms.
• Working knowledge of networking fundamentals (TCP/IP, DNS, DHCP, VLANs).
• Strong troubleshooting skills and the ability to explain technical issues clearly to non-technical users.
• Self-directed and comfortable working independently.
• Reliable transportation and ability to be onsite daily.
• Someone who is a team player and would assist other team members in other departments with other administrative tasks.

Responsibilities

• Provide Level 1 through Level 3 technical support for staff, in person.
• Set up, configure, and maintain workstations, laptops, printers, and peripherals.
• Manage user accounts, permissions, and onboarding/offboarding.
• Administer Microsoft 365, including email, file sharing, and security settings.
• Support network infrastructure including switches, firewalls, Wi-Fi, and VPN.
• Troubleshoot and support lab equipment, instrument PCs, and connected systems.
• Maintain backups, patching, endpoint protection, and asset inventory.
• Document procedures and work with outside vendors and service providers as needed.
• Help support data integrity and compliance practices in a regulated environment.

Skills

IT support

Help desk

Systems administration

Networking basics

Troubleshooting

Independent work

Team player

Education

Bachelors degree

Tools

Windows

macOS

Active Directory/Entra ID

Microsoft 365 / Office 365

Networking (TCP/IP, DNS, DHCP, VLANs)

Job description

JLSa2 Therapeutics is seeking a hands-on IT professional to support our growing team in a startup environment. The role starts as part-time onsite (≈20 hours/week, 9am-1pm or 10am-2:30pm) and will transition to full-time as the company scales.

You will handle day-to-day IT support, workstation setup, AD/Entra ID, Microsoft 365, and network infrastructure, with responsibilities expanding as we grow. The ideal candidate is highly organized, an independent self-starter, and a team player in a