Molecular Diagnostics QC Scientist - Liquid Biopsy

nRichDX Inc.; Irvine (CA); On-site; USD 85,000 - 120,000; Full time

Job summary

nRichDX Inc. is seeking a Scientist to join our R&D team in Irvine, focusing on quality control and functional testing of nucleic-acid extraction kits for cfDNA/cfRNA workflows.

You will contribute to routine workflows, verification, troubleshooting, and data generation for ongoing product development and manufacturing support. The role requires hands-on molecular biology experience, strong documentation, and collaboration with Manufacturing, Quality, and R&D to ensure reliable kit performance

Qualifications

• B.S. in Molecular Biology, Biochemistry, Chemistry, Biomedical Engineering, or related field (M.S. preferred).
• 2+ years hands-on experience in a molecular biology lab (industry preferred).
• Demonstrated experience with DNA/RNA extraction and qPCR/RT‑qPCR.
• Strong attention to detail and comfort working in a structured, repeatable testing environment.
• Ability to produce clear documentation and communicate results to cross‑functional teams.
• Preferred: automation experience with Hamilton Star; cfDNA/cfRNA/cfTNA workflows.
• Familiarity with GxP/ISO concepts, change control, deviations, and data integrity principles.
• Comfortable analyzing data in Excel; bonus for basic stats/graphing or scripting.

Responsibilities

• Own and execute functional testing plans for commercial kit lots (incoming components, in‑process, and final kit performance testing).
• Run routine QC assays, including TapeStation/Bioanalyzer, extraction performance checks, and carryover/contamination controls.
• Prepare and process biological samples (plasma/urine/whole blood) according to SOPs.
• Track lot performance, generate QC summaries/CoA‑support data, and flag out‑of‑spec trends.
• Investigate deviations and failures, perform root‑cause analysis, and recommend corrective actions with R&D, Manufacturing, and Quality.
• Partner with Manufacturing to ensure smooth tech transfer and readiness for scale.
• Coordinate with Quality on documentation, change control support, and release criteria.
• Support troubleshooting of customer‑reported issues by recreating conditions and documenting findings.
• Assist with protocol optimization, method verification, and robustness studies.
• Support automation workflows as needed (e.g., Hamilton or internal platforms), including run setup, execution, and data review.
• Maintain lab organization, instrument upkeep, reagent preparation, and inventory management.
• Maintain high‑quality documentation: lab notebooks, raw data files, SOP updates, and summary reports.

Skills

Highly organized

Strong troubleshooting

Documentation skills

Cross-functional collaboration

Detail-oriented

Education

B.S. in Molecular Biology, Biochemistry, Chemistry, Biomedical Engineering, or related field

M.S. preferred

Tools

TapeStation/Bioanalyzer

qPCR/RT-qPCR

NGS library QC

Hamilton Star automation

Job description

nRichDX Inc. is seeking a Scientist to join our R&D team in Irvine, focusing on quality control and functional testing of nucleic-acid extraction kits for cfDNA/cfRNA workflows.

You will contribute to routine workflows, verification, troubleshooting, and data generation for ongoing product development and manufacturing support. The role requires hands-on molecular biology experience, strong documentation, and collaboration with Manufacturing, Quality, and R&D to ensure reliable kit performance