Lead cfDNA Bioinformatician — Remote Diagnostics & Pipelines

Scorpion Therapeutics; United States; Remote; USD 131,000 - 164,000; Full time

Job summary

Scorpion Therapeutics is seeking a Lead Bioinformatician to develop algorithms for cfDNA-based diagnostic assays for Women’s and Organ health. You will design, benchmark, and deploy methods to detect variants in challenging sequencing contexts, including low-fraction samples, and guide call-sets and quality standards across teams.

The role emphasizes cross-functional collaboration with Variant Management, Reporting, and Laboratory Operations to ensure data quality and regulatory readiness in a

Qualifications

• Bachelor’s degree in Bioinformatics, Computational Biology, Human Genetics, or related field.
• 4+ years’ experience analyzing short-read sequencing data in regulated or production-adjacent settings.
• Proficiency in Python and experience benchmarking bioinformatics methods for difficult regions.

Responsibilities

• Lead algorithm development for cfDNA-based diagnostic assays.
• Benchmark callers and deploy computational methods for low-fraction samples.
• Collaborate with Variant Management, Reporting, and Laboratory Operations to ensure data quality and integration.

Skills

Python

cfDNA analysis

Genomics

Education

Bachelor’s degree in Bioinformatics, Computational Biology, Human Genetics, or related field

Job description

Scorpion Therapeutics is seeking a Lead Bioinformatician to develop algorithms for cfDNA-based diagnostic assays for Women’s and Organ health. You will design, benchmark, and deploy methods to detect variants in challenging sequencing contexts, including low-fraction samples, and guide call-sets and quality standards across teams.

The role emphasizes cross-functional collaboration with Variant Management, Reporting, and Laboratory Operations to ensure data quality and regulatory readiness in a