Molecular & Cellular Biologist I - CHO & Omics Research

Joulé; Andover (MA); On-site; USD 65,000 - 85,000; Full time

Job summary

System One, including Joulé, is seeking a Molecular and Cellular Biologist I for onsite work in Andover, MA. The role focuses on applying multi-omics and systems biology to improve mammalian cell culture for recombinant protein production.

The position requires a Bachelor’s or Master’s degree with 0–2 years of relevant lab experience, strong experimental design, and proficiency in mammalian cell culture and molecular biology techniques.

Qualifications

• Bachelor’s or Master’s degree in molecular biology, cell biology, biochemistry, biotechnology, bioengineering, systems biology, or a related field required.
• 0-2 years of relevant laboratory or biotechnology-industry experience.
• Strong experimental design, analytical thinking, and problem solving.
• Proficiency in mammalian cell culture and molecular biology techniques (e.g., aseptic technique, transfection, DNA/RNA extraction, PCR, qPCR, cloning, sequencing, immunoblotting, FACS, microscopy).
• Familiarity with multi-omics study design, bioinformatics, statistical analysis, and systems biology.
• Effective written and verbal communication and ability to work in multidisciplinary teams.

Responsibilities

• Design and execute molecular and cellular biology experiments involving CHO cell cultures to generate substrate for multi-omics analyses.
• Design and execute experiments to examine gene copies, transcript levels, protein folding, assembly, trafficking, secretion, and degradation.
• Analyze and interpret data using statistical, bioinformatics, and pathway-analysis tools.
• Document findings and prepare technical reports, presentations, and manuscripts.
• Collaborate with cell-line development scientists, bioprocess engineers, analytical scientists, and computational biologists.
• Comply with laboratory safety and data-integrity requirements.

Skills

Experimental design

Mammalian cell culture

Molecular biology techniques

Bioinformatics & statistics

Team collaboration

Education

Bachelor’s or Master’s degree in molecular biology or related field

Tools

PCR/qPCR

DNA/RNA extraction

Immunoblotting

FACS

Microscopy

Job description

System One, including Joulé, is seeking a Molecular and Cellular Biologist I for onsite work in Andover, MA. The role focuses on applying multi-omics and systems biology to improve mammalian cell culture for recombinant protein production.

The position requires a Bachelor’s or Master’s degree with 0–2 years of relevant lab experience, strong experimental design, and proficiency in mammalian cell culture and molecular biology techniques.