Scientist I: CHO Cell Line Development & Monoclonal Screening

Creative Solutions Services, LLC; South San Francisco (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

US Tech Solutions in South San Francisco, CA is seeking a Scientist I/II to join a collaborative team developing CHO cell lines for GMP applications. The role involves hands-on CHO cell line development and characterization studies, scaling from 96-well plates to shake flasks, and cross-functional collaboration to drive projects forward.

The ideal candidate will have experience with genetic and molecular characterization, as well as instrumentation such as flow cytometers, HPLC, and automated

Responsibilities

• Lead end-to-end CHO cell line development workflows from transfection to screening and scale-up.
• Perform single-cell cloning to establish monoclonal CHO cell lines and bank cell lines.
• Engineer DNA vectors for expressing antibodies and novel protein formats; perform DNA/RNA analysis.
• Operate and maintain instruments including ViCell, Octet, flow cytometers, ambr15, HPLC, and automated imagers.
• Present updates at cross-functional meetings and collaborate with purification, analytical, and formulation teams.
• Maintain meticulous electronic lab notebooks (ELNs) with data integrity.

Skills

CHO cell line development

Flow cytometry

Tools

ViCell

Octet

Flow cytometers

ambr15

HPLC

Automated imagers

Job description

US Tech Solutions in South San Francisco, CA is seeking a Scientist I/II to join a collaborative team developing CHO cell lines for GMP applications. The role involves hands-on CHO cell line development and characterization studies, scaling from 96-well plates to shake flasks, and cross-functional collaboration to drive projects forward.

The ideal candidate will have experience with genetic and molecular characterization, as well as instrumentation such as flow cytometers, HPLC, and automated