Molecular and Cellular Biologist - I

Spectraforce Technologies, Inc.; Andover (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

Spectraforce Technologies, Inc. is seeking a Molecular and Cellular Biologist I to support multi-omics and systems biology approaches in CHO cell culture for recombinant protein production. The role emphasizes rigorous experimentation and data reporting in a collaborative, regulated lab.

The ideal candidate has 0–2 years of lab experience and a Bachelor’s or Master’s degree in a related field, with strong communication and teamwork skills to thrive in a multidisciplinary setting.

Qualifications

• Bachelor's or Master's degree in molecular biology, cell biology, biochemistry, biotechnology, bioengineering, systems biology, or a related field required.
• 0 to 2 years of relevant laboratory or biotechnology-industry experience.
• Experience with mammalian and/or CHO cell culture, antibody production, multi-omics technologies, molecular perturbation methods, and regulated laboratory environments is preferred.

Responsibilities

• Design and execute molecular and cellular biology experiments involving the transfection, passaging, and sampling of CHO cell cultures to generate substrate for multi-omics analyses.
• Design and execute experiments to examine gene copies, transcript levels, protein folding, assembly, trafficking, secretion, and degradation.
• Analyze and interpret data using statistical, bioinformatics, and pathway-analysis tools.
• Document findings and prepare technical reports, presentations, and manuscripts.
• Collaborate with cell-line development scientists, bioprocess engineers, analytical scientists, and computational biologists.
• Comply with laboratory safety and data-integrity requirements.

Skills

Mammalian cell culture

Molecular biology techniques

Aseptic technique

Transfection

PCR

qPCR

Immunoblotting

FACS

Microscopy

DNA/RNA extraction

Multi-omics study design

Bioinformatics

Statistical analysis

Systems biology

Molecular cell biology

DNA replication

Transcription

Translation

Proteostasis

Metabolism

Cellular stress

Recombinant protein production

Written communication

Verbal communication

Team collaboration

Experimental rigor

Documentation

Reproducibility

Scientific integrity

Education

Bachelor's or Master's degree

Job description

Job Title: Molecular and Cellular Biologist - I

Location: Andover, MA 01810

Duration: 12 Months (Possibility of extension depending upon business requirements and performance)

Summary

The Molecular and Cellular Biologist will support efforts to apply multi-omics & systems biology approaches to improve mammalian cell culture performance for the production of recombinant proteins.

Job Responsibilities

• Design and execute molecular and cellular biology experiments involving the transfection, passaging, and sampling of CHO cell cultures to generate substrate for multi-omics analyses.
• Design and execute experiments to examine gene copies, transcript levels, protein folding, assembly, trafficking, secretion, and degradation.
• Analyze and interpret data using statistical, bioinformatics, and pathway-analysis tools.
• Document findings and prepare technical reports, presentations, and manuscripts.
• Collaborate with cell-line development scientists, bioprocess engineers, analytical scientists, and computational biologists.
• Comply with laboratory safety and data-integrity requirements.

Skills

• Strong experimental design, analytical thinking, and problem-solving skills.
• Proficiency in mammalian cell culture and molecular biology techniques (e.g. aseptic technique, cell transfection, DNA/RNA extraction, PCR, qPCR, electrophoresis, molecular cloning, DNA/RNA sequencing, immunoblotting, FACS, microscopy).
• Familiarity with multi-omics study design, bioinformatics, statistical analysis, and systems biology.
• Strong understanding of molecular cell biology fundamentals including DNA replication, transcription, translation, proteostasis, metabolism, cellular stress mechanisms, and their relation to recombinant protein production.
• Effective written and verbal communication.
• Ability to work well and collaboratively within multidisciplinary teams.
• Strong attention to experimental rigor, documentation, reproducibility, and scientific integrity.

Education/Experience

• Bachelor's or Master's degree in molecular biology, cell biology, biochemistry, biotechnology, bioengineering, systems biology, or a related field required.
• 0 to 2 years of relevant laboratory or biotechnology-industry experience.
• Experience with mammalian and/or CHO cell culture, antibody production, multi-omics technologies, molecular perturbation methods, and regulated laboratory environments is preferred.