Metabolomics/Lipidomics Scientist - LC-MS Expert

BPGbio, Inc.; Waltham (MA); On-site; USD 100,000 - 160,000; Full time

Job summary

BPGbio, Inc. in Waltham, MA seeks a Metabolomics/Lipidomics Scientist with extensive MS-based experience to lead targeted and non-targeted bioanalysis using LC/MS and LC/MS/MS platforms.

You will conceptualize experiments, develop novel methods, perform analyses on diverse biological samples, maintain instruments, and contribute to SOPs, QA/QC, and external collaborations, reporting results to management.

Qualifications

• Ph.D. in analytical chemistry, biochemistry, or a related field with MS experience.
• Broad understanding of metabolomics/lipidomics applications in disease contexts such as neurodegeneration, obesity, cardiovascular disease, and cancer.
• Proven ability to troubleshoot common instrumentation issues, specifically for HPLC and MS systems.
• Experience with sample preparation techniques including SPE, liquid-liquid extraction and protein precipitation for biofluids, tissues and cells.
• Deep understanding of core LC and MS concepts, including MS/MS, isotope dilution, isotopologue identification, and high-resolution mass strategies.
• Excellent communication and organizational skills with detail-focused record-keeping.
• Knowledge of MS Office (Word, Excel, PowerPoint) for reports.

Responsibilities

• Conceptualize, perform, analyze and report experiments.
• Perform mass spectrometry-based assays on diverse samples.
• Laboratory instrumentation maintenance and QA/QC.
• Develop SOPs and system suitability tests.
• Manage external collaborations.
• Other duties as assigned.

Skills

Mass spectrometry

LC-MS

Method development

SOP development

QA/QC

Scientific communication

Team collaboration

Education

Ph.D. in analytical chemistry or related field

Tools

HPLC

MS instrumentation

SPE

Job description

BPGbio, Inc. in Waltham, MA seeks a Metabolomics/Lipidomics Scientist with extensive MS-based experience to lead targeted and non-targeted bioanalysis using LC/MS and LC/MS/MS platforms.

You will conceptualize experiments, develop novel methods, perform analyses on diverse biological samples, maintain instruments, and contribute to SOPs, QA/QC, and external collaborations, reporting results to management.