Metabolomics & Lipidomics Scientist II

Genentech, Inc.; South San Francisco (CA); On-site; USD 86,000 - 159,000; Full time

Job summary

Genentech, Inc. in South San Francisco seeks a Scientist II in the Small Molecule Biomarkers team (Metabolomics & Lipidomics) within DMPK. You will execute high-throughput mass spectrometry workflows and apply modern tools—including Generative AI—to drive biological insights for drug discovery.

This on-site role entails LC-MS methods, automation, data analysis, and collaboration across multidisciplinary teams, with a salary range and discretionary bonus potential.

Qualifications

• Bachelor’s or Master’s degree in biological, chemical, pharmaceutical sciences, or related field.
• 5+ years (Bachelor’s) or 3+ years (Master’s) in biotech/pharma.
• Proven LC-MS assays for endogenous metabolites or lipids.
• Experience with LC-MS platforms (UHPLC, QQQ, HRMS).
• Aptitude with Generative AI tools for coding and analysis.

Responsibilities

• Perform onsite LC-MS workflow methods to acquire biomarker data.
• Use automation for sample prep across biofluids, tissues, and cells.
• Process MS data and run AI/ML workflows for analysis.
• Maintain rigorous QC and documentation for study reports.
• Support lab operations, maintenance, safety, and compliance.

Skills

LC-MS

Data analysis

Generative AI

Biochemistry

Team collaboration

Education

Bachelor’s degree

Master’s degree

Tools

UHPLC

Triple quadrupole

HRMS

Analytical software

Job description

Genentech, Inc. in South San Francisco seeks a Scientist II in the Small Molecule Biomarkers team (Metabolomics & Lipidomics) within DMPK. You will execute high-throughput mass spectrometry workflows and apply modern tools—including Generative AI—to drive biological insights for drug discovery.

This on-site role entails LC-MS methods, automation, data analysis, and collaboration across multidisciplinary teams, with a salary range and discretionary bonus potential.