Manufacturing Technician 4 - 1st Shift

The businesses of Merck KGaA, Darmstadt, Germany; St. Louis (MO); On-site; USD 40,000 - 75,000; Full time

Job summary

An established industry player is seeking a Manufacturing Technician 4 to join their team in a cGMP regulated environment. This role involves preparing buffer formulations for API manufacturing, ensuring compliance with safety and quality standards, and maintaining equipment. As a key contributor, you will support operations, train new staff, and engage in continuous process improvement initiatives. If you are passionate about manufacturing and thrive in a collaborative team, this opportunity is perfect for you. Join a forward-thinking company that values innovation and quality in the pharmaceutical industry.

Qualifications

• At least 6 months experience in a pharmaceutical GMP environment.
• Knowledge of FDA, EMA, and other regulatory standards.

Responsibilities

• Prepare buffer formulations supporting Drug Substance manufacturing.
• Execute daily tasks following cGMPs and document activities accurately.
• Train new employees and participate in process improvement initiatives.

Skills

GMP Compliance

Buffer Formulation

Process Improvement

Mechanical Aptitude

Documentation Skills

Education

High School Diploma or GED

Tools

Windows Word

Excel

PowerPoint

Job description

Work Location:

St. Louis, Missouri

Shift:

1st shift, Monday – Friday, 6:00am – 2:30pm (some flexibility with schedule)

Department:

LS-SC-POKMD1A GMP MFG Support - Buffers and Facility

Recruiter:

Erin Wilson

Note:

This information is for internal use only. Please do not share outside of the organization.

Your Role:

At MilliporeSigma, as a Manufacturing Technician 4 at our Cherokee Site (3300 S. Second Ave, St. Louis), you will safely execute, develop new approaches, and support operations in a cGMP regulated environment for API (Active Pharmaceutical Ingredients) manufacturing teams. Your responsibilities include maintaining equipment, preparing solutions, staging equipment and supplies, and other manufacturing support activities. The primary focus will be creating buffer formulations to support Drug Substance manufacturing. Job duties include:

1. Prepare buffer formulations supporting Drug Substance manufacturing, emphasizing safety and quality, and maintain cleanliness through scheduled cleaning activities.
2. Execute daily tasks following cGMPs and approved operating procedures, accurately documenting all activities, including logbook maintenance, in accordance with GDP standards.
3. Safely dispose of cleaning and process waste following approved procedures, and maintain safe stock levels of supplies and gowning materials using the Kanban system.
4. Ensure compliance with Safety and Quality guidelines by adhering to procedures, assisting in their development, performing safety inspections, and contributing to quality deviations as needed.
5. Support department operations and goals by training new employees, assisting with daily functions, and participating in process improvement, safety, quality, and 6S initiatives, working closely with the supervisor.

Physical Attributes:

• Stand for extended periods.
• Lift, push, or pull up to 50 lbs.
• Wear PPE including masks, safety shoes, gloves, Tyvek suits, and respirators.

Who You Are

Minimum Qualifications:

• High school diploma or GED.
• At least 6 months experience in a pharmaceutical GMP environment (Manufacturing, Quality, MSAT).

Preferred Qualifications:

• Experience in API manufacturing.
• Strong mechanical aptitude.
• Experience with process improvement.
• Knowledge of FDA, EMA, and other regulatory standards.
• Proficiency with computer applications such as Windows Word, Excel, PowerPoint.

Equal Employment Opportunity Statement:

The company is an Equal Employment Opportunity employer. Discrimination based on race, color, religion, age, sex, sexual orientation, national origin, disability, veteran status, genetic information, gender identity, marital status, or any other protected class is prohibited. Concerns of discrimination should be reported to HR, Legal, or Compliance. The company will not retaliate against individuals reporting discrimination in good faith.