LNP & mRNA R&D Intern

Sartorius AG; Marlborough (MA); On-site; USD 34,000 - 41,000; Full time

Benefits offered by this job

Mentoring programs

Internal seminars

Global collaboration

Smart facilities

Job summary

Sartorius AG is seeking a motivated graduate student to conduct IVT experiments on benchtop bioreactors and develop protocols for nucleic acid–loaded LNP formulations at our Marlborough, MA site. You will support LNP process development, including screening, scale-up, and workflow optimization, while troubleshooting experimental designs and communicating results in internal meetings.

Ideal candidates have hands-on RNA synthesis experience and familiarity with LNP formulation techniques, plus

Qualifications

• Current graduate student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.
• Hands-on laboratory experience with RNA synthesis, preferably including in vitro transcription.
• Experience with LNP formulation and characterization, including techniques such as DLS, NTA, RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA, or related assays.
• Familiarity with microfluidic instruments, laboratory automation, 3D printing, advanced cell models, or conjugation reactions is a plus.
• Strong oral and written communication skills, with the ability to summarize results and present findings clearly.
• Identification with our core values: Sustainability, Openness, Enjoyment.

Responsibilities

• Conduct systematic experiments of IVT reactions on benchtop bioreactors and analyze data.
• Develop and execute protocols for preparing and characterizing nucleic acid–loaded LNP formulations using automated platforms.
• Support LNP process development, including screening, scale-up, and workflow optimization.
• Troubleshoot issues with experimental design and execution.
• Collect, analyze, and interpret data; prepare technical summaries and present results in internal reviews.

Skills

RNA synthesis

In vitro transcription

LNP formulation

DLS

NTA

HPLC

Capillary electrophoresis

ELISA

Laboratory automation

Communication

Education

Graduate student in biomedical/chemical/mechanical engineering

Tools

3D printing

Microfluidics

Conjugation reactions

Job description

Sartorius AG is seeking a motivated graduate student to conduct IVT experiments on benchtop bioreactors and develop protocols for nucleic acid–loaded LNP formulations at our Marlborough, MA site. You will support LNP process development, including screening, scale-up, and workflow optimization, while troubleshooting experimental designs and communicating results in internal meetings.

Ideal candidates have hands-on RNA synthesis experience and familiarity with LNP formulation techniques, plus