Lipid Nanoparticle & mRNA Synthesis Intern - Marlborough, MA

Sartorius North America; Marlborough (MA); On-site; USD 25,000 - 41,000; Full time

Benefits offered by this job

Mentoring programs

Internal seminars

Virtual onboarding

Job summary

Sartorius Marlborough, MA is seeking a Research Intern (Lipid Nanoparticle & mRNA Synthesis) to contribute to the full product development cycle from concept to prototype and work closely with engineers and scientists in a multidisciplinary environment. The role is onsite at Marlborough.

Responsibilities include conducting IVT experiments, developing LNP formulations, supporting process development, troubleshooting, data analysis, and presenting results in internal meetings.

Qualifications

• Current graduate student in biomedical, chemical, mechanical engineering or related field with experience in lipid nanoparticles and/or nucleic acids.
• Hands-on lab experience with RNA synthesis, preferably including in vitro transcription.
• Experience with LNP formulation/characterization using standard assays (DLS, NTA, RiboGreen, HPLC, ELISA).
• Familiarity with lab automation, microfluidics, or 3D printing is a plus.
• Strong written and oral communication skills; ability to present results clearly.

Responsibilities

• Conduct systematic IVT experiments on benchtop bioreactors; collect and analyze data.
• Develop protocols for preparing and characterizing nucleic acid-loaded LNP formulations.
• Support LNP process development, scale-up, and workflow optimization.
• Troubleshoot experimental design and execution.
• Collect, analyze, and interpret data; present results in internal meetings.

Skills

RNA synthesis

IVT/ Transcription

LNP formulation

Microfluidics

Lab automation

Communication

Team collaboration

Education

Graduate student in biomedical/chemical/mechanical engineering

Tools

DLS

NTA

RiboGreen assay

HPLC

Capillary electrophoresis

ELISA

Job description

Sartorius is a leading technology provider to the life sciences and biopharma industries, actively shaping dynamic, innovative, and high growth markets to support better health for more people.
As a Research Intern (Lipid Nanoparticle & mRNA Synthesis), you will contribute to the full product development cycle-from concept to prototype-and collaborate closely with engineers and scientists in a multidisciplinary environment.

*Onsite role based at our Marlborough, MA site*

What you will accomplish together with us:

• Conduct systematic experiments of in vitro transcription (IVT) reaction on benchtop bioreactors; collect and analyze the data.

• Develop and execute protocols for preparing and characterizing nucleic acid-loaded lipid nanoparticle (LNP) formulations using automated LNP synthesis platforms.

• Support LNP process development activities, including screening, scale-up, and manufacturing-relevant workflow optimization.

• Troubleshoot issues with experimental design and execution.

• Collect, analyze, and interpret experimental data; prepare technical summaries and present results in internal meetings and reviews.

What will convince us:

Education

• Current graduate student in biomedical, chemical, mechanical engineering, or related field with formal education and experience with lipid nanoparticles and/or nucleic acids.

Experience

• Hands-on laboratory experience with RNA synthesis, preferably including in vitro transcription.

• Experience with LNP formulation and characterization, including techniques such as dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA, or related assays. Ideal to have an experience with one or more of the following: dynamic light scattering (DLS), nanoparticle tracking analysis, RiboGreen assay, HPLC, chromatography, capillary electrophoresis, ELISA

• Familiarity with microfluidic instruments, laboratory automation, 3D printing, advanced cell models, or conjugation reactions is a plus.

• Strong oral and written communication skills, with the ability to summarize results and present findings clearly.

• Identification with our core values: Sustainability, Openness, Enjoyment

Compensation is up to $30 an hour. No relocation and/or accommodations are offered.

What We Offer

As a growing global life science company, with our stock listed on the German DAX and TecDAX, Sartorius offers a wide range of benefits:
Personal and Professional Development: Mentoring, leadership programs, internal seminar offerings
Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform
Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as "Coaching", "Agile Working" and a "Businesswomen's Network"
Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.

Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability or based on status in any other protected group of class.

Please view equal employment opportunity posters provided by OFCCP here.

E-Verify Participation Info

E-Verify Workers Rights

Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at [e-mail]

Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability, or based on status in any other protected group of class.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at [e-mail]

About Sartorius

Sartorius is part of the solution in the fight against cancer, dementia, and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster, so that new therapeutics can reach patients worldwide.

We look for ambitious team players and creative minds, who want to contribute to this goal and advance their careers in a dynamic global environment.