LNP Lab Specialist: mRNA Encapsulation & Purification

BioSpace; Redmond (WA); On-site; USD 55,000 - 65,000; Full time

Benefits offered by this job

Free colleague meals during shift

Onsite massages Charis

Onsite gyms

Job summary

GenScript USA Inc./ProBio Inc. seeks a candidates to join a dynamic biotech team in Redmond, WA. You will encapsulate a variety of genetic payloads, including mRNA, with lipids, and ensure high-quality downstream processing and documentation.

The role involves LNP purification, in-process QC, and final product preparation for shipment in a fast-paced setting. Collaboration across disciplines and strong communication are essential for success.

Qualifications

• Bachelor's degree in Chemical Engineering, Biology, or related field.
• Experience with mRNA or Lipid Nanoparticles (LNP) is a definite plus.
• Techniques such as PCR, HPLC, or enzymatic reactions are highly desired.
• Ability to work in a small cross-disciplinary team in a fast-paced environment.
• Strong communication with peers and managers.

Responsibilities

• Encapsulate a range of genetic payloads (mRNA, Circular RNA, sgRNA) in diverse lipids.
• Perform LNP purification and concentration per SOPs (ultrafiltration, TFF, sterile filtration, FPLC).
• Carry out antibody-decorated LNP processes and related purification per SOPs.
• Do in-process QC for LNP size, zeta, PDI, encapsulation, and maintain documentation per ISO 9001.
• Conduct particle size and zeta measurements for quality assurance.
• Prepare final product for shipment, including filtration, aliquot filling, labeling.

Skills

mRNA/LNP experience

PCR

HPLC

Team collaboration

Adaptability

Effective communication

Education

Bachelors in Chemical Engineering

Bachelors in Biology or related field

Tools

PCR

HPLC

Enzymatic reactions

Job description

GenScript USA Inc./ProBio Inc. seeks a candidates to join a dynamic biotech team in Redmond, WA. You will encapsulate a variety of genetic payloads, including mRNA, with lipids, and ensure high-quality downstream processing and documentation.

The role involves LNP purification, in-process QC, and final product preparation for shipment in a fast-paced setting. Collaboration across disciplines and strong communication are essential for success.