LNP Lab Technician

BioSpace; Redmond (WA); On-site; USD 55,000 - 65,000; Full time

Benefits offered by this job

Free colleague meals during shift

Onsite massages Charis

Onsite gyms

Job summary

GenScript USA Inc./ProBio Inc. seeks a candidates to join a dynamic biotech team in Redmond, WA. You will encapsulate a variety of genetic payloads, including mRNA, with lipids, and ensure high-quality downstream processing and documentation.

The role involves LNP purification, in-process QC, and final product preparation for shipment in a fast-paced setting. Collaboration across disciplines and strong communication are essential for success.

Qualifications

• Bachelor's degree in Chemical Engineering, Biology, or related field.
• Experience with mRNA or Lipid Nanoparticles (LNP) is a definite plus.
• Techniques such as PCR, HPLC, or enzymatic reactions are highly desired.
• Ability to work in a small cross-disciplinary team in a fast-paced environment.
• Strong communication with peers and managers.

Responsibilities

• Encapsulate a range of genetic payloads (mRNA, Circular RNA, sgRNA) in diverse lipids.
• Perform LNP purification and concentration per SOPs (ultrafiltration, TFF, sterile filtration, FPLC).
• Carry out antibody-decorated LNP processes and related purification per SOPs.
• Do in-process QC for LNP size, zeta, PDI, encapsulation, and maintain documentation per ISO 9001.
• Conduct particle size and zeta measurements for quality assurance.
• Prepare final product for shipment, including filtration, aliquot filling, labeling.

Skills

mRNA/LNP experience

PCR

HPLC

Team collaboration

Adaptability

Effective communication

Education

Bachelors in Chemical Engineering

Bachelors in Biology or related field

Tools

PCR

HPLC

Enzymatic reactions

Job description

About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

About GenScript

Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation in biotech and healthcare by providing researchers and companies with the building blocks needed to develop groundbreaking treatments and products. Guided by its mission to Make People and Nature Healthier Through Biotechnology, and its role as a well-recognized biotechnology company, GenScript has a team of approximately 6,165 employees and has served more than 200,000 customers across over 100 countries and regions.

Job Description

Are you ready to join a dynamic and innovative team on the cutting edge of biotechnology? We are looking for a skilled individual to play a crucial role in our mission. As a key member of our team, you will have the opportunity to work on exciting projects involving the encapsulation and purification of mRNA and genetic payloads, ensuring the highest quality standards throughout the entire process.

Key Responsibilities

• Advanced Payload Encapsulation: Expertly encapsulate a range of genetic payloads, including mRNA, Circular RNA, and sgRNA, within a diverse array of lipids.
• Precise Purification and Concentration: Follow LNP downstream processing SOP to perform LNP purification and concentrating. Related technical skill include but not limit to ultrafiltration, TFF, sterile filtration, and FPLC methods.
• Performing complicate antibody decorated LNP process and related purification process following SOP guidance
• In process QC for LNP size, zeta, PDI, encapsulation efficiency measure and others, make sure following good documentation rule and take care for details
• Nanoparticle Quality Assurance: Conduct quality checks on particle size and zeta potential to ensure the highest standards of quality and performance.
• Final Product Preparation: Prepare the final product for shipment, including filtering, aliquot filling, and affixing labels to shipping tubes.
• Standard Operating Procedures (S.O.P.) Compliance: Strictly adhere to production S.O.P.s to maintain consistency, quality to validated processes.
• Thorough Documentation: Maintain comprehensive records accordance to ISO 9001 of all processes and materials used in the production.
• Inventory Management: Keep track of inventory using our management system, and proactively order materials as needed for production.
• High Throughput and Accuracy: Quickly and accurately perform tasks in high repetition.

Qualifications

• Educational Background: Possess a Bachelor's degree in Chemical Engineering, Biology, or a related field in Chemistry.
• Relevant Experience: Prior experience working with mRNA or Lipid Nanoparticles (LNP) is a definite plus.
• Technical Proficiency: Experience with techniques such as PCR, HPLC, or enzymatic reactions is highly desired.
• Team Collaboration: The ability to work effectively as part of a small cross-disciplinary team is essential to achieve both short-term and long-term goals.
• Adaptability: Experience in a fast-paced, high-demand environment is highly desirable.
• Effective Communication: The capability to communicate with peers and managers in a polite and concise manner is a valuable asset.

Benefit

• Medical Insurance/ Vision Insurance/ Dental Insurance
• 401(k) & Retirement Savings Plan (RSP)
• Short Term Disability Insurance
• New Child Leave
• Paid Time Off
• Paid Company Holidays per year
• Paid Sick Days (earned based on hours worked)
• Compassionate Leave
• Jury Duty Leave
• Float day
• Personal days

Perks

• Free colleague meals during shift
• Onsite massages Charis
• Onsite gyms

Compensation

Salary range: $55,000 – $65,000 total compensation, including bonus, depending on experience and qualifications.

Benefits

Benefits include medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and company holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.