QC Technician - RNA/LNP Production

3M HEALTHCARE; Redmond (WA); On-site; USD 55,000 - 65,000; Full time

Benefits offered by this job

Free colleague meals during shift

Onsite massages Charis

Onsite gyms

Job summary

GenScript USA Inc./ProBio Inc. is seeking a detail-oriented QC Technician to join the mRNA&LNP Service Team. You will perform analytical testing and quality control assays to ensure the integrity, purity, potency, and consistency of mRNA products and lipid nanoparticle formulations.

You will collaborate with R&D, Manufacturing, QA and Project management teams to support client projects and internal process improvements, while maintaining rigorous documentation and timely QC reporting.

Qualifications

• Bachelor's degree in molecular biology, chemistry, biochemistry, pharmaceutical science or related field.
• Experience with HPLC, LC-MS, ELISA, cell culture, and flow cytometry is preferred.
• Ability to communicate efficiently verbally and in writing.
• Ability to follow detailed instructions, maintain accurate records and notes, and adhere to safe lab practices.
• Able to work in a fast-paced environment with high throughput.

Responsibilities

• Support analytical testing and QC assays to ensure integrity, purity, potency of mRNA products and LNP formulations.
• Report out-of-specification results and assist with investigations and root cause analysis.
• Ensure timely completion of QC reports and maintain good documentation practices.
• Monitor supply inventory and maintain an organized work area and storage spaces.
• Collaborate with R&D, Manufacturing, QA, and Project management teams to support projects.

Skills

Communication skills

Attention to detail

Fast-paced work

Documentation practices

Education

Bachelor's degree in molecular biology/chemistry/biochemistry/pharmaceutical science

Tools

HPLC

LC-MS

ELISA

Cell culture

Flow cytometry

Job description

About GenScript

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.

GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.

GenScript is a global leader in life sciences research tools and services, providing innovative solutions in gene synthesis, protein expression, antibody development, and cutting-edge mRNA&LNP technologies. Our mRNA&LNP Services team delivers end-to-end solutions for vaccine and therapeutic development — from sequence design and IVT mRNA synthesis to LNP formulation, analytics, and QC release testing.

We are seeking a detail-oriented and technically skilled QC Technician to join our rapidly growing mRNA&LNP Service Team. In this role, you will perform analytical testing and quality control assays to ensure the integrity, purity, potency, and consistency of mRNA products and lipid nanoparticle formulations. You will work closely with R&D, Manufacturing team, QA and Project management teams to support client projects and internal process improvements.

Responsibilities:

• Responsible for supporting communication with production manager and team, contributing to a working environment that encourages employee involvement and collaboration.
• Conduct analytical assays including but not limited to:
• RNA concentration and purity (UV spectrophotometry, fluorometry)
• RNA integrity (Agilent Bioanalyzer, gel electrophoresis)
• dsRNA contamination (ELISA, immunoblot, HPLC)
• LNP particle size and polydispersity (DLS, others)
• Encapsulation efficiency (ribogreen assay, dye exclusion)
• Endotoxin testing
• pH, osmolality, sterility (as applicable)
• Reports out-of-specification results and deviations to the manager. Assists with investigations, root cause analysis, and reports for out-of-specification results and deviations.
• Responsible for timely completion of QC report after production job is finished. Accountable for the QC report compliance with good documentation practices.
• Support process improvement initiatives within scope of responsibility.
• Monitors supply inventory and identifies any products required.
• Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner.
• Perform other duties as needed.

Requirements:

• Bachelor's degree in molecular biology, chemistry, biochemistry, pharmaceutical science or related field, master’s is preferred.
• Experience with HPLC, LC-MS, ELISA, cell culture, and flow cytometry is preferred.
• Ability to communicate efficiently verbally and in writing.
• Ability to perform in a fast-paced environment with high product throughput.
• Ability to follow detailed instructions, maintain accurate records and notes, and carry out assignments in a thorough, conscientious fashion while adhering to safe laboratory practices.

A sense of humility and an eagerness to continue to learn and contribute to a supportive team.

Benefit:

• Medical Insurance/Vision Insurance/Dental Insurance
• 401(k) & Retirement Savings Plan (RSP)
• Short Term Disability Insurance
• New Child Leave
• Paid Time Off
• Paid Company Holidays per year
• Paid Sick Days (earned based on hours worked)
• Compassionate Leave
• Jury Duty Leave
• Float day
• Personal days

Perks:

• Free colleague meals during shift
• Onsite massages Charis
• Onsite gyms

Compensation: Salary range: $55,000 – $65,000 total compensation, including bonus, depending on experience and qualifications.

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.