Lead Systems Engineer — Biomedical Cloud & Interop

Leidos; Reston (VA); On-site; USD 108,000 - 195,000; Full time

Job summary

The Leidos Health & Civil Sector seeks a Systems Engineer Lead to support NIH/NCI biomedical research environments. You will oversee enterprise integration, cloud infrastructure, platform operations, and security-focused implementation activities.

Working with program managers, government stakeholders, and SMEs, you will architect, integrate, and operate scalable systems, guide modernization initiatives, and ensure high availability and compliance across federal standards.

Qualifications

• Bachelor's degree in Computer Science, Information Systems, Engineering, or related field.
• 8+ years of experience with at least 6 years in complex integrated systems.
• Experience supporting large Federal IT modernization or systems integration programs.
• Experience with Agile development and DevSecOps practices.
• Excellent written and verbal communication skills.
• Ability to obtain Federal suitability or security requirements.
• Ability to obtain Public Trust / ADPII Clearance.

Responsibilities

• Provide technical and operational leadership within the specified functional area.
• Collaborate with Government stakeholders to define priorities, roadmaps, and delivery schedules.
• Lead systems engineering for enterprise applications, cloud platforms, and shared services across the NCI enterprise.
• Develop system architecture, integration strategies, infrastructure roadmaps, and modernization plans.
• Design, implement, and maintain secure, scalable hybrid cloud and on-prem environments.
• Oversee systems integration across applications, data platforms, AI/ML services, IAM, and partner systems.
• Lead modernization initiatives involving virtualization, containers, Kubernetes, IaC, and automation.
• Ensure performance, resilience, DR, and operational monitoring of enterprise systems.
• Guide cybersecurity practices, Zero Trust, encryption, and compliance with NIH/HHS security requirements.
• Support HPC and cloud-based research environments and data storage platforms.
• Document architecture, interface control, procedures, baselines, and standards.
• Provide leadership during architecture reviews and mentoring of engineers.
• Support Agile planning, backlog refinement, sprints, and releases.
• Coordinate cross-functional teams to resolve technical issues.

Skills

Agile development

DevSecOps

Federal IT modernization

Communication skills

Security clearance

Public Trust/ADPII

System integration

Education

Bachelor's degree

Tools

Azure

Azure DevOps

Kubernetes

REST APIs

Git

CI/CD

Cloud-native architectures

Job description

The Leidos Health & Civil Sector seeks a Systems Engineer Lead to support NIH/NCI biomedical research environments. You will oversee enterprise integration, cloud infrastructure, platform operations, and security-focused implementation activities.

Working with program managers, government stakeholders, and SMEs, you will architect, integrate, and operate scalable systems, guide modernization initiatives, and ensure high availability and compliance across federal standards.