Lead Scientist, Antibody Discovery & Optimization

Mosaic Biosciences, Inc.; Boulder (CO); Presencial; USD 120.000 - 135.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Health and dental insurance

Disability and life insurance

401k with company match

Bonus opportunities

Descripción de la vacante

Mosaic Biosciences, Inc. seeks a Sr. Scientist I to join the Antibody Discovery and Optimization team in Boulder, CO. The candidate will lead antibody discovery campaigns, drive strategy, and mentor a small team in a fast-paced, collaborative setting.

Required expertise includes yeast display, PhD or MS with extensive experience, PCR/ cloning, and strong data interpretation skills. In-person lab work in Boulder is expected.

Formación

• PhD or MS with extensive industry experience and 4+ years in related field.
• Demonstrated antibody discovery experience.
• Hands-on yeast display systems experience.

Responsabilidades

• Independently design and execute antibody discovery campaigns using yeast and phage display.
• Construct and optimize libraries using PCR, RT-PCR, and mutagenesis in display vectors.
• Direct high-throughput screening using flow cytometry and establish evaluation criteria.
• Analyze complex data to guide project decisions and outcomes.
• Lead collaborations with external partners and prepare updates and reports.
• Manage multiple projects, timelines, risks, and deliverables for therapeutic leads.
• Collaborate with Protein Science, Protein Engineering, Sequencing, and Project Leadership.
• Contribute to proposals with feasibility assessments and resource estimates.
• Mentor scientists and lead a small team as needed.
• Maintain organized ELN and LIMS documentation and ensure quality.

Conocimientos

Antibody discovery

Yeast display

Flow cytometry

PCR / cloning

Project leadership

Scientific communication

Data analysis

Mentorship

Independent work

NGS analysis

Educación

PhD in molecular biology/biochemistry

MS in related field

Herramientas

ELN

LIMS

NGS analysis tools

Flow cytometer

Descripción del empleo

Mosaic Biosciences, Inc. seeks a Sr. Scientist I to join the Antibody Discovery and Optimization team in Boulder, CO. The candidate will lead antibody discovery campaigns, drive strategy, and mentor a small team in a fast-paced, collaborative setting.

Required expertise includes yeast display, PhD or MS with extensive experience, PCR/ cloning, and strong data interpretation skills. In-person lab work in Boulder is expected.