Lead Researcher: Leukemia Modeling & Translational Science

Thecentermemphis; Memphis (TN); On-site; USD 90,000 - 130,000; Full time

Job summary

St. Jude Children's Research Hospital in Memphis is seeking a Lead Researcher to investigate the biologic basis of fusion oncoprotein-driven acute lymphoblastic leukemia (ALL).

The role involves leading collaborative efforts spanning leukemia biology, molecular biology, structural biology, and translational science. You will oversee in vitro and in vivo leukemia modeling, proteomics, genomics, and functional assays, contributing to translational targets within an NCI-supported program.

Qualifications

• Bachelor's degree in a relevant scientific area.
• 5+ years of research experience.
• Experience with in vivo studies or cancer models is desirable.
• Hands-on experience in molecular and cell biology techniques.

Responsibilities

• Perform molecular and cell biology experiments to investigate mechanisms.
• Conduct DNA/RNA isolation, PCR-based assays, and Western blotting.
• Perform flow cytometry and functional assays to evaluate phenotypes and responses.
• Contribute to fusion oncoprotein-driven leukemia modeling in vitro and in vivo.
• Apply proteomics, structural biology, and functional genomics to identify targets.
• Analyze, interpret, and document experimental data.
• Collaborate with multidisciplinary teams to develop therapies for pediatric leukemia.

Skills

Molecular biology

Cell culture

Flow cytometry

PCR

Western blotting

Proteomics

Genomics

Experimental design

Education

Bachelor's degree

Tools

Flow cytometer

Job description

St. Jude Children's Research Hospital in Memphis is seeking a Lead Researcher to investigate the biologic basis of fusion oncoprotein-driven acute lymphoblastic leukemia (ALL).

The role involves leading collaborative efforts spanning leukemia biology, molecular biology, structural biology, and translational science. You will oversee in vitro and in vivo leukemia modeling, proteomics, genomics, and functional assays, contributing to translational targets within an NCI-supported program.