Lead Researcher: In Vivo & In Vitro Drug Screening

St. Jude Children's Research Hospital; Memphis (TN); On-site; USD 60,000 - 105,000; Full time

Job summary

St. Jude Children’s Research Hospital in Memphis, TN is seeking a Lead Researcher to advance therapeutic approaches for pediatric cancers, with a focus on leukemia and medulloblastoma.

You will lead in vitro and in vivo drug screening, design dose–response and synergy studies, and apply molecular and cellular assays to define mechanisms of drug response and support translational progress.

Qualifications

• Bachelor’s degree in a relevant scientific field is required.
• 5+ years of research experience is required.
• 3+ years of experience with a Master’s degree.
• No prior experience required with a PhD.
• Strong knowledge of techniques and research methods used in lab settings.
• Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred.

Responsibilities

• Lead and perform in vitro and in vivo drug screening studies.
• Design and execute dose-response, viability, and drug-synergy studies.
• Develop, optimize, and troubleshoot cell-based and molecular assays.
• Utilizes short- and long-read RNA-seq and other genomics approaches to investigate mechanisms of therapeutic response.
• Analyze and interpret experimental data, prioritize candidates to advance studies toward in vivo validation.
• Design and/or coordinate in vivo efficacy studies.
• Maintain comprehensive and well-organized experimental records.

Skills

Molecular biology

Cell culture

Flow cytometry

RNA sequencing

Drug screening

In vivo studies

Western blotting

Genomics

Education

Bachelor’s degree

Job description

St. Jude Children’s Research Hospital in Memphis, TN is seeking a Lead Researcher to advance therapeutic approaches for pediatric cancers, with a focus on leukemia and medulloblastoma.

You will lead in vitro and in vivo drug screening, design dose–response and synergy studies, and apply molecular and cellular assays to define mechanisms of drug response and support translational progress.