Lead LC-MS/MS Scientist, GLP Bioanalysis Production

Kcasbio; Kansas City (MO); On-site; USD 90,000 - 140,000; Full time

Benefits offered by this job

Stock ownership program

KCAS University (career development)

Volunteer time off

Job summary

KCAS Bio, a fast-growing CRO based in Kansas City, MO, seeks a Sr. Scientist to lead Mass Spec Bioanalysis in a GLP-regulated environment. You will oversee study setup through reporting, troubleshoot issues, and ensure data integrity while maintaining client communication.

The role focuses on LC-MS/MS workflows, sample prep, data review, and audit support. You will mentor junior staff, interact with QA, and contribute to audits and regulatory inspections.

Qualifications

• Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, or related field with at least 5 years of experience in a bioanalytical laboratory environment
• Extensive hands-on experience working in a GLP-regulated laboratory environment (required)
• Strong experience with bioanalytical sample preparation and quantitative LC-MS/MS workflows
• Experience executing regulated studies, including data review, reporting, and audit support
• Demonstrated ability to troubleshoot technical and operational issues in a production environment
• Experience interacting with Quality Assurance and supporting audits and inspections
• Prior experience acting as a study lead or Principal Investigator–type role preferred

Responsibilities

• Execute and oversee all phases of assigned studies including sample preparation, LC-MS/MS analysis, data review, and report generation in a regulated environment
• Act as lead scientist on studies, providing work direction, technical guidance, and training to junior scientific staff
• Be responsible for all client communication related to study conduct and data delivery
• Interact with QAU to resolve audit findings, deviations, and compliance-related issues
• Have final authority for sample identification, including resolution of discrepancies with clinical sites and/or clients
• Be accountable for study timelines, deliverables, and communication of status to management and clients
• Ensure compliance of all study activities with study protocols, SOPs & GLP regulatory requirements
• Review and ensure accuracy, completeness, and integrity of data prior to reporting
• Support audit readiness and participate in client and regulatory inspections as needed
• Act as a technical resource for troubleshooting assay performance and operational challenges within a production environment
• Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

Education

Bachelor’s/Master’s/PhD in Chemistry or Biochemistry or related field

Tools

LC-MS/MS

Job description

KCAS Bio, a fast-growing CRO based in Kansas City, MO, seeks a Sr. Scientist to lead Mass Spec Bioanalysis in a GLP-regulated environment. You will oversee study setup through reporting, troubleshoot issues, and ensure data integrity while maintaining client communication.

The role focuses on LC-MS/MS workflows, sample prep, data review, and audit support. You will mentor junior staff, interact with QA, and contribute to audits and regulatory inspections.