Global PK/PD & Pharmacometrics Executive Director

BioSpace; Indianapolis (IN); Hybrid; USD 180,000 - 240,000; Full time

Job summary

Lilly, headquartered in Indianapolis, Indiana, seeks a Director – Executive Director for PK/PD & Pharmacometrics to lead quantitative pharmacology across Drug Discovery and Development. The role emphasizes model-informed drug discovery, cross-functional collaboration, and regulatory interactions to accelerate medicine development.

You will guide project teams, oversee early- through late-stage PK/PD analyses, and drive data-driven decisions.

Qualifications

• PhD in a relevant discipline and at least 8 years of experience in PK/PD or Clinical Pharmacology
• Experience with pharmacokinetics/pharmacodynamics, pharmacometrics, and clinical pharmacology principles
• Experience with regulatory interactions (FDA/EMA/PMDA) preferred

Responsibilities

• Provide PK/PD and quantitative clinical pharmacology leadership to project teams
• Conduct exploratory MIDD, PK/PD analyses across development stages
• Lead and support study protocols, analysis plans, data analysis and interpretation
• Prepare INDs, IBs, CTDs and regulatory documents for multiple geographies
• Communicate quantitative data clearly and advocate for model-based decision making
• Coach and mentor scientists within the department
• Represent the group in publications and scientific organizations

Skills

Cross-functional collaboration

Communication of quantitative concepts

Regulatory interactions

Leadership and mentoring

Scientific leadership

Education

PhD in a relevant discipline

Tools

PK/PD modeling

Regulatory documentation

Job description

Lilly, headquartered in Indianapolis, Indiana, seeks a Director – Executive Director for PK/PD & Pharmacometrics to lead quantitative pharmacology across Drug Discovery and Development. The role emphasizes model-informed drug discovery, cross-functional collaboration, and regulatory interactions to accelerate medicine development.

You will guide project teams, oversee early- through late-stage PK/PD analyses, and drive data-driven decisions.