Global Head, PK/PD & Pharmacometrics

Initial Therapeutics, Inc.; Indianapolis (IN); Hybrid; USD 190,000 - 250,000; Full time

Job summary

Lilly in Indianapolis or Bracknell is hiring a Director – Executive Director, PK/PD & Pharmacometrics to lead model-informed drug discovery and development across portfolios. You will guide target selection, dosing strategies, patient populations, and development plans with strong cross‑functional collaboration.

You will perform exploratory MIDD analyses, mentor scientists, and communicate quantitative results to senior stakeholders while interacting with regulatory agencies to enable

Qualifications

• PhD in PK/PD or Clinical Pharmacology or related discipline.
• Strong leadership in PK/PD and pharmacometrics.
• Proven ability to collaborate across functions and communicate quantitative concepts.

Responsibilities

• Provide PK/PD scientific leadership to project teams to support target/molecule/dose/strategy decisions.
• Lead exploratory MIDD analyses across development stages.
• Drive data‑driven decision making and solve high‑level drug development challenges.
• Lead and integrate PK/PD in program and product team plans; contribute to study protocols and reports.
• Prepare regulatory documents and interact with FDA/EMA/PMDA as needed.
• Mentor and coach colleagues; promote external visibility through publications and collaborations.

Job description

Lilly in Indianapolis or Bracknell is hiring a Director – Executive Director, PK/PD & Pharmacometrics to lead model-informed drug discovery and development across portfolios. You will guide target selection, dosing strategies, patient populations, and development plans with strong cross‑functional collaboration.

You will perform exploratory MIDD analyses, mentor scientists, and communicate quantitative results to senior stakeholders while interacting with regulatory agencies to enable