Executive Medical Director, Immunology Clinical Development

Vertex Pharmaceuticals Incorporated; Boston (MA); Hybrid; USD 320,000 - 480,000; Full time

Job summary

Vertex Pharmaceuticals Incorporated seeks an Executive Medical Director, Clinical Development to lead the povetacicept immunology franchise. You will shape the clinical development strategy, oversee global programs, and provide medical expertise across Regulatory, Safety, Operations, and Business Development.

You will drive collaboration across Research, Regulatory, Medical Affairs, and Commercial teams, ensuring rigorous study design, safety monitoring, and data interpretation while positioning

Qualifications

• Requires comprehensive understanding of the drug development process from Phase 1 to Phase 4.
• Strong leadership of multidisciplinary teams across global development.
• Experience planning and executing global clinical development activities.
• Experience interacting with regulatory authorities and shaping regulatory strategy.

Responsibilities

• Develop study protocols and oversee clinical development programs.
• Review safety data and manage medical monitoring of studies.
• Interface with international regulatory authorities to support development objectives.
• Lead cross-functional teams in preparing briefing books for regulatory interactions.
• Ensure compliance with GCP and Vertex SOPs in all activities.

Skills

Clinical development leadership

People management

Immunology expertise

Regulatory interfacing

Strategic portfolio thinking

Education

Board certification/eligibility in immunology or rheumatology

15+ years pharmaceutical industry experience

Job description

Vertex Pharmaceuticals Incorporated seeks an Executive Medical Director, Clinical Development to lead the povetacicept immunology franchise. You will shape the clinical development strategy, oversee global programs, and provide medical expertise across Regulatory, Safety, Operations, and Business Development.

You will drive collaboration across Research, Regulatory, Medical Affairs, and Commercial teams, ensuring rigorous study design, safety monitoring, and data interpretation while positioning