Director, Immunology & Cell Therapy Strategy

Vertex Pharmaceuticals; Boston (MA); On-site; USD 238,000 - 357,000; Full time

Job summary

Vertex Pharmaceuticals is seeking a Senior Director of Immunology in Boston to drive strategy and execution across multiple immunology research programs and the cell and genetic therapy portfolio. The role collaborates with manufacturing and development teams to enable transformative advances and to guide critical investment decisions.

The position requires deep immunology expertise, strategic leadership, and a track record of leading cross-functional teams from discovery through IND, with

Qualifications

• PhD/MD in immunology or related field.
• 12+ years of industry or equivalent experience in Immunology.
• Experience supervising others and leading cross-functional teams, contributing to discovery and development programs to IND, FIM and PoC.

Responsibilities

• Serve as Research Program Team Lead for 2+ programs driving cross-functional collaboration and alignment to achieve program goals.
• Develop strategy and build capabilities to advance novel, next gen drug discovery in T1D.
• Provide scientific, strategic, and organizational leadership for immunology research and drug discovery programs supporting the cell and genetic therapy portfolio.
• Develop and execute innovative immunomodulatory and translational immunology strategies to advance allogeneic transplantation and other immune-mediated therapeutic opportunities.
• Lead cross-functional teams to identify, validate, and advance novel therapeutic targets and candidates from discovery through development while ensuring timely, high-quality execution and communication of research results.
• Shape research and portfolio strategy through deep immunology expertise, data-driven conclusions, emerging scientific advances, and balanced pursuit of innovation against defined project objectives.
• Build and maintain productive collaborations across internal functions and with external academic, clinical, industry, and pharma partners.
• Manage group resources, budgets, hiring, staff activities, and goal setting to align scientific capabilities and personnel priorities with department and corporate objectives.
• Mentor and develop high-performing scientists while fostering scientific rigor, ethical publication and patenting practices, and clear communication across the organization.

Skills

Immunology expertise

Translational science

Immunology-driven drug discovery

Cross-functional leadership

Biomarker development

Allogeneic transplantation

In vivo/ex vivo translational

Flow cytometry

RNA-seq

Leadership

Education

PhD/MD in immunology or related field

Tools

Flow cytometry

Immunohistochemistry

ELISA

RNA-seq

Cell sorting

Epigenetics

Job description

Vertex Pharmaceuticals is seeking a Senior Director of Immunology in Boston to drive strategy and execution across multiple immunology research programs and the cell and genetic therapy portfolio. The role collaborates with manufacturing and development teams to enable transformative advances and to guide critical investment decisions.

The position requires deep immunology expertise, strategic leadership, and a track record of leading cross-functional teams from discovery through IND, with