Director, PKDM: Small Molecule Portfolio Strategy

BioSpace; South San Francisco (CA); Hybrid; USD 250,000 - 360,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental and vision coverage

Life and disability insurance

Flexible spending accounts

Bonus program

Stock-based long-term incentives

Generous time-off plans

Job summary

Amgen seeks a Director of PKDM - Small Molecule Portfolio Strategy & Leadership to lead cross-functional PKDM-BA activities from discovery through regulatory submission. You will guide portfolio strategy, influence critical development decisions, and drive successful advancement of small molecule programs.

You will collaborate with therapeutic areas, develop scientific strategies, and mentor teams to foster excellence and innovation across Amgen’s portfolio.

Qualifications

• Doctorate or professional degree with industry experience in pharmaceutical sciences or pharmacokinetics.
• Experience leading small molecule PKDM programs and regulatory submissions.
• Strong leadership across matrixed teams and external partners.

Responsibilities

• Provide PKDM-BA leadership for small molecule discovery and development programs.
• Drive cross-functional teams through scientific innovation and risk assessment.
• Lead submissions to INDs/NDAs and interactions with authorities.
• Define strategies for candidate selection, optimization, and registration.
• Mentor scientific talent and shape PKDM-BA capabilities across Amgen.

Skills

PKDM leadership

Regulatory submissions

Cross-functional leadership

Drug disposition expertise

Education

PhD

PharmD

MD with experience

Masters in related field

Bachelors in related field

Job description

Amgen seeks a Director of PKDM - Small Molecule Portfolio Strategy & Leadership to lead cross-functional PKDM-BA activities from discovery through regulatory submission. You will guide portfolio strategy, influence critical development decisions, and drive successful advancement of small molecule programs.

You will collaborate with therapeutic areas, develop scientific strategies, and mentor teams to foster excellence and innovation across Amgen’s portfolio.