Director, Oncology Translational Biomarkers

GlaxoSmithKline

Waltham (MA)

On-site

USD 190,000 - 316,000

Full time

5 days ago
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Job summary

GlaxoSmithKline is seeking a Director of Oncology Translational Medicine, Clinical Biomarkers, to lead biomarker and translational medicine strategies supporting late-stage oncology asset development. You will collaborate with the Clinical Biomarker Executive Director, driving biomarker-driven decision-making and patient stratification.

You will leverage cutting-edge technologies to validate biomarkers, align biomarker strategy with clinical plans, and work with matrix teams to influence design,

Qualifications

  • Ph.D. or equivalent with 7+ years or M.Sc. with 10+ years of drug development experience in pharma, with oncology biomarkers and translational research.
  • Strong expertise in cancer biology and clinical development across solid tumors and hematologic malignancies.
  • Experience leading cross-functional teams and designing strategic biomarker plans including regulated assays.
  • Experience conducting clinical trials and working in clinical study teams.
  • Translational biomarker plans and on-boarding innovative technologies.

Responsibilities

  • Drive design and execution of clinical biomarker and translational medicine strategies for oncology.
  • Validate and implement biomarker strategies for clinical programs to support patient stratification and dose selection.
  • Participate in tumor-specific Biomarker Matrix teams and collaborate with internal/external stakeholders.
  • Represent Translational Medicine to establish biomarker-driven criteria in study designs.
  • Define biomarker priorities and generate evidence packages from real-world and clinical data.
  • Oversee sample testing plans and deliver high-quality biomarker data for regulatory strategies.

Skills

biomarker strategies
translational medicine
cross-functional leadership
clinical trials
NGS
flow cytometry
PCR
IHC/IF

Education

Ph.D. or equivalent
M.D., Ph.D. or equivalent

Tools

Regulated biomarker assays
NGS
FISH
PCR
IHC/IF

Job description

GlaxoSmithKline is seeking a Director of Oncology Translational Medicine, Clinical Biomarkers, to lead biomarker and translational medicine strategies supporting late-stage oncology asset development. You will collaborate with the Clinical Biomarker Executive Director, driving biomarker-driven decision-making and patient stratification.

You will leverage cutting-edge technologies to validate biomarkers, align biomarker strategy with clinical plans, and work with matrix teams to influence design,

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