Director of Translational Oncology & Biomarker Strategy

ALX Oncology

South San Francisco (CA)

Hybrid

USD 240,000 - 260,000

Full time

14 days+

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Benefits offered by this job

Stock programs

Performance-based bonus

401K

Job summary

ALX Oncology in South San Francisco, CA, seeks a Director of Translational Oncology to develop and execute translational and clinical biomarker strategies across its oncology portfolio. You will partner with Clinical Development, Biostatistics, Regulatory, and external collaborators to define patient selection, pharmacodynamic biomarkers, and combination strategies.

The role emphasizes leadership of biomarker components in trials, CRO and lab partner management, and clear communication of

Qualifications

PhD, MD, or MD/PhD in oncology or related field with ~10 years in biotech/pharma.
Experience supporting oncology drug development from translational medicine perspective.
Proven ability to lead translational/biomarker strategies and integrate with endpoints.
Experience managing CROs and laboratory partners for sample handling and data transfer.

Responsibilities

Develop and execute translational and clinical biomarker strategies for oncology programs.
Lead biomarker components of trials, including protocol development and stratification.
Oversight of CROs and lab partners; evaluate assays and platforms.
Collaborate with Clinical Development to integrate with sample collection and data transfer.
Translate biomarker data into actionable development strategies; contribute to regulatory documents.
Represent ALX's translational science externally and foster collaborations.