Director of Enterprise AI Architecture

Pfizer; San Diego (CA); On-site; USD 163,000 - 272,000; Full time

Benefits offered by this job

Relocation assistance

Job summary

Pfizer is seeking a Director, Senior Technical Architect to lead architecture and technology strategy for ELT-level AI programs. You will translate ambitious AI goals into practical architectures, driving enterprise alignment, security, and scalable design.

You will mentor teams, set governance, and partner with senior Digital leaders to deliver measurable outcomes at enterprise scale. On-site work strongly preferred with relocation support available.

Qualifications

• Bachelor’s degree with at least 8 years of experience; OR a Master’s with 7+ years; OR a PhD with 5+ years of experience.
• Demonstrated experience defining the architecture and technology strategy for significant programs, products, or technology domains — ideally AI or data-intensive.
• Deep, hands-on technical expertise in modern engineering practices, cloud platforms, data and integration patterns, APIs, AI/ML services, security, and reliability.
• Experience acting as a technical advisor or design authority, guiding teams and stakeholders through influence rather than direct authority.
• Experience partnering with senior business and Digital stakeholders on high-visibility programs to shape technical direction and measurable outcomes.

Responsibilities

• Shape the architecture and technology strategy for ELT-level AI programs, aligning with enterprise standards.
• Define target and reference architectures, establishing standards, integration patterns, and guardrails.
• Connect AI program architecture to Pfizer’s platforms, reusing shared capabilities and integrating into the platform spine.
• Serve as trusted advisor to senior leaders, translating ambitions into practical architecture choices and delivery models.
• Define how AI, automation, and modern engineering practices are architected with governance and verification.
• Provide architectural leadership and mentorship to program engineering teams.
• Establish reliability, security, documentation, and operational excellence across architectures.

Skills

Architectural leadership

AI program architecture

Enterprise architecture

Stakeholder influence

Cloud platforms

Data integration

Security & reliability

Education

Bachelor's degree with 8+ years

Master's degree with 7+ years

PhD with 5+ years

Tools

APIs

Data platforms

Security frameworks

Job description

Pfizer is seeking a Director, Senior Technical Architect to lead architecture and technology strategy for ELT-level AI programs. You will translate ambitious AI goals into practical architectures, driving enterprise alignment, security, and scalable design.

You will mentor teams, set governance, and partner with senior Digital leaders to deliver measurable outcomes at enterprise scale. On-site work strongly preferred with relocation support available.