Contract Scientist/Sr. Scientist – In Vivo Pharmacology and NGS

Commonwealth Sciences, Inc.; Boston (MA); Presencial; USD 110.000 - 170.000; Jornada completa

Descripción de la vacante

Commonwealth Sciences, Inc. is seeking a Scientist or Senior Scientist with in vivo pharmacology and next-generation sequencing (NGS) experience to support preclinical research programs.

The candidate will work with animal tissues and apply sequencing approaches to characterize drug responses, collaborating with discovery and bioinformatics teams. Responsibilities include designing in vivo studies, processing tissue samples, applying RNA/DNA isolation and sequencing workflows, and presenting

Formación

• Ph.D. or equivalent in Pharmacology, Biology, Molecular Biology, Genetics or related field.
• Industry or academic experience in in vivo pharmacology/preclinical research.
• Hands-on experience with NGS and/or transcriptomic/genomic analysis.
• Experience with animal tissues and samples from in vivo studies.
• Familiarity with RNA/DNA isolation, library preparation, sequencing technologies, and data analysis.

Responsabilidades

• Design and execute in vivo pharmacology studies to evaluate efficacy, pharmacodynamics, and MOA.
• Collect, process, and analyze animal tissue samples from preclinical studies.
• Apply NGS-based approaches to analyze gene expression and genomic changes in tissues.
• Collaborate with bioinformatics and discovery teams to interpret sequencing data.
• Develop and optimize tissue processing, extraction, and sequencing workflows.
• Present experimental results to cross-functional project teams.
• Contribute to study design, data interpretation, and preparation of reports.

Conocimientos

In vivo pharmacology

NGS sequencing

RNA isolation

Genomics analysis

Transcriptomics

Experimental design

Data interpretation

Communication

Educación

Ph.D. or equivalent

Herramientas

RNA extraction

Library preparation

Sequencing technologies

Descripción del empleo

Contract Scientist/Sr. Scientist – In Vivo Pharmacology and NGS

We are seeking a Scientist or Senior Scientist with experience in in vivo pharmacology and next-generation sequencing (NGS) to support preclinical research programs. The ideal candidate will have hands-on experience working with animal tissue samples and applying NGS or genomic sequencing approaches to characterize biological responses to drug candidates.

Responsibilities:

• Design and execute in vivo pharmacology studies to evaluate drug efficacy, pharmacodynamics, and mechanisms of action.
• Collect, process, and analyze animal tissue samples from preclinical studies.
• Apply NGS-based approaches to analyze gene expression, genomic, or transcriptomic changes in tissue samples.
• Collaborate with bioinformatics, molecular biology, and discovery teams to interpret sequencing data.
• Develop and optimize tissue processing, RNA/DNA extraction, and sequencing workflows.
• Analyze and present experimental results to cross-functional project teams.
• Contribute to study design, data interpretation, and preparation of reports and presentations.
• Maintain accurate experimental records and ensure studies are conducted in accordance with applicable laboratory and regulatory standards.

Requirements:

• Ph.D. or equivalent advanced degree in Pharmacology, Biology, Molecular Biology, Genetics, or a related discipline.
• Industry or academic experience in in vivo pharmacology/preclinical research.
• Hands-on experience with NGS and/or transcriptomic/genomic analysis.
• Experience working with animal tissues and samples from in vivo studies.
• Familiarity with RNA/DNA isolation, library preparation, sequencing technologies, and/or sequencing data analysis.
• Strong experimental design, data analysis, and communication skills.