Contract Scientist: In Vivo Pharmacology & NGS

Commonwealth Sciences, Inc.; Boston (MA); On-site; USD 110,000 - 170,000; Full time

Job summary

Commonwealth Sciences, Inc. is seeking a Scientist or Senior Scientist with in vivo pharmacology and next-generation sequencing (NGS) experience to support preclinical research programs.

The candidate will work with animal tissues and apply sequencing approaches to characterize drug responses, collaborating with discovery and bioinformatics teams. Responsibilities include designing in vivo studies, processing tissue samples, applying RNA/DNA isolation and sequencing workflows, and presenting

Qualifications

• Ph.D. or equivalent in Pharmacology, Biology, Molecular Biology, Genetics or related field.
• Industry or academic experience in in vivo pharmacology/preclinical research.
• Hands-on experience with NGS and/or transcriptomic/genomic analysis.
• Experience with animal tissues and samples from in vivo studies.
• Familiarity with RNA/DNA isolation, library preparation, sequencing technologies, and data analysis.

Responsibilities

• Design and execute in vivo pharmacology studies to evaluate efficacy, pharmacodynamics, and MOA.
• Collect, process, and analyze animal tissue samples from preclinical studies.
• Apply NGS-based approaches to analyze gene expression and genomic changes in tissues.
• Collaborate with bioinformatics and discovery teams to interpret sequencing data.
• Develop and optimize tissue processing, extraction, and sequencing workflows.
• Present experimental results to cross-functional project teams.
• Contribute to study design, data interpretation, and preparation of reports.

Skills

In vivo pharmacology

NGS sequencing

RNA isolation

Genomics analysis

Transcriptomics

Experimental design

Data interpretation

Communication

Education

Ph.D. or equivalent

Tools

RNA extraction

Library preparation

Sequencing technologies

Job description

Commonwealth Sciences, Inc. is seeking a Scientist or Senior Scientist with in vivo pharmacology and next-generation sequencing (NGS) experience to support preclinical research programs.

The candidate will work with animal tissues and apply sequencing approaches to characterize drug responses, collaborating with discovery and bioinformatics teams. Responsibilities include designing in vivo studies, processing tissue samples, applying RNA/DNA isolation and sequencing workflows, and presenting