Clinical Pharmacology & MIDD Strategy Lead

Zai Lab, Ltd.; South San Francisco (CA); On-site; USD 198,000 - 257,000; Full time

Job summary

Zai Lab, Ltd. seeks an Associate Director to lead Clinical Pharmacology & MIDD for assigned programs in South San Francisco, guiding PK/PD, PBPK and translational modeling across development stages.

The role integrates quantitative insights into dose selection, study design, and regulatory planning, with senior leadership exposure and external collaborations. Strong communication and cross-functional leadership are essential.

Qualifications

• 10+ years in clinical pharmacology, pharmacometrics, MIDD or related quantitative sciences.
• Experience supporting drug development programs and regulatory submissions.
• Demonstrated leadership in modeling activities and cross-functional collaboration.

Responsibilities

• Lead Clinical Pharmacology & MIDD strategy from early development to registration.
• Develop and execute integrated PK/PD and MIDD plans for programs.
• Design and interpret clinical pharmacology studies and translational analyses.
• Communicate findings to senior leadership and health authorities.

Skills

Clinical pharmacology

MIDD

PK/PD

PBPK

Translational modeling

QSP

Regulatory interactions

Leadership

Education

BS in Clinical Pharmacology

PhD in Pharmacology or related field

Tools

NONMEM

Monolix

Simcyp

GastroPlus

R

Job description

Zai Lab, Ltd. seeks an Associate Director to lead Clinical Pharmacology & MIDD for assigned programs in South San Francisco, guiding PK/PD, PBPK and translational modeling across development stages.

The role integrates quantitative insights into dose selection, study design, and regulatory planning, with senior leadership exposure and external collaborations. Strong communication and cross-functional leadership are essential.