Clinical Pharmacology Lead: MIDD & PK/PD Strategy

Pfizer Belgium; New York (NY); Hybrid; USD 139,000 - 232,000; Full time

Benefits offered by this job

401(k) plan with company match

Health benefits

Relocation assistance

Job summary

Pfizer seeks an Associate Director in Clinical Pharmacology to advance Internal Medicine programs using model‑informed drug development. You will lead PK/PD analyses, design dose strategies, and provide regulatory pharmacology support across development teams.

You will collaborate with clinicians, statisticians, and scientists to ensure optimal development plans and robust decision making in a hybrid, on-site setting in the U.S.

Qualifications

• Breadth of leadership capable of influencing peers and coaching others.
• Strong quantitative skills in mechanistic PK/PD modeling and simulations.
• Experience applying quantitative pharmacology to development decisions.
• Proven ability to interact with regulatory teams and clinical groups.
• Demonstrated track record in cross-functional collaboration.

Responsibilities

• Act as Clinical Pharmacology representative on cross-functional teams.
• Lead clinical pharmacology deliverables for assigned projects.
• Design and oversee PK/PD analyses and dosing strategies.
• Develop End-to-End MIDD plans for development programs.
• Collaborate with clinicians and statisticians on dose-ranging.
• Contribute to regulatory documents and inquiries.
• Coach junior colleagues and stay current with guidelines.

Skills

Leadership

Quantitative PK/PD modeling

Clinical pharmacology

Regulatory interactions

Cross-functional collaboration

MIDD concepts

Project leadership

Communication skills

Education

MD/PhD or equivalent in pharmacokinetics/pharmacometrics

PharmD or equivalent training/experience

Industry experience in pharmacology/pharmacometrics

Tools

NONMEM

R

PK/PD analysis tools

Job description

Pfizer seeks an Associate Director in Clinical Pharmacology to advance Internal Medicine programs using model‑informed drug development. You will lead PK/PD analyses, design dose strategies, and provide regulatory pharmacology support across development teams.

You will collaborate with clinicians, statisticians, and scientists to ensure optimal development plans and robust decision making in a hybrid, on-site setting in the U.S.